6ZOL

SARS-CoV-2-Nsp1-40S complex, focused on head

Summary for 6ZOL

• Entry DOI: 10.2210/pdb6zol/pdb
• EMDB information: 11322
• Descriptor: 18S ribosomal RNA, 40S ribosomal protein S19, 40S ribosomal protein S20, ... (18 entities in total)
• Functional Keywords: inhibitor, mrna channel, 40s ribosomal subunit, translation
• Biological source: Homo sapiens; More
• Total number of polymer chains: 16
• Total formula weight: 854316.87

Authors

Schubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.-A.,Leibundgut, M.L.,Thiel, V.,Muehlemann, O.,Ban, N. (deposition date: 2020-07-07, release date: 2020-07-22, Last modification date: 2021-02-10)

• Primary citation: Schubert, K.,Karousis, E.D.,Jomaa, A.,Scaiola, A.,Echeverria, B.,Gurzeler, L.A.,Leibundgut, M.,Thiel, V.,Muhlemann, O.,Ban, N.; SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.; Nat.Struct.Mol.Biol., 27:959-966, 2020; PubMed: 32908316; DOI: 10.1038/s41594-020-0511-8

Experimental method

ELECTRON MICROSCOPY (2.8 Å)