6ZOL

SARS-CoV-2-Nsp1-40S complex, focused on head

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
D	0002181	biological_process	cytoplasmic translation
D	0003677	molecular_function	DNA binding
D	0003684	molecular_function	damaged DNA binding
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
D	0004520	molecular_function	DNA endonuclease activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005759	cellular_component	mitochondrial matrix
D	0005783	cellular_component	endoplasmic reticulum
D	0005819	cellular_component	spindle
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0005856	cellular_component	cytoskeleton
D	0005886	cellular_component	plasma membrane
D	0005925	cellular_component	focal adhesion
D	0006281	biological_process	DNA repair
D	0006284	biological_process	base-excision repair
D	0006412	biological_process	translation
D	0006413	biological_process	translational initiation
D	0006417	biological_process	regulation of translation
D	0006915	biological_process	apoptotic process
D	0006974	biological_process	DNA damage response
D	0007059	biological_process	chromosome segregation
D	0008017	molecular_function	microtubule binding
D	0010628	biological_process	positive regulation of gene expression
D	0014069	cellular_component	postsynaptic density
D	0015631	molecular_function	tubulin binding
D	0015935	cellular_component	small ribosomal subunit
D	0016020	cellular_component	membrane
D	0016829	molecular_function	lyase activity
D	0017148	biological_process	negative regulation of translation
D	0019104	molecular_function	DNA N-glycosylase activity
D	0019899	molecular_function	enzyme binding
D	0019900	molecular_function	kinase binding
D	0019901	molecular_function	protein kinase binding
D	0022626	cellular_component	cytosolic ribosome
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0030544	molecular_function	Hsp70 protein binding
D	0031116	biological_process	positive regulation of microtubule polymerization
D	0031334	biological_process	positive regulation of protein-containing complex assembly
D	0031397	biological_process	negative regulation of protein ubiquitination
D	0032079	biological_process	positive regulation of endodeoxyribonuclease activity
D	0032357	molecular_function	oxidized purine DNA binding
D	0032358	molecular_function	oxidized pyrimidine DNA binding
D	0032587	cellular_component	ruffle membrane
D	0032743	biological_process	positive regulation of interleukin-2 production
D	0034614	biological_process	cellular response to reactive oxygen species
D	0042104	biological_process	positive regulation of activated T cell proliferation
D	0042981	biological_process	regulation of apoptotic process
D	0044390	molecular_function	ubiquitin-like protein conjugating enzyme binding
D	0044877	molecular_function	protein-containing complex binding
D	0045202	cellular_component	synapse
D	0045738	biological_process	negative regulation of DNA repair
D	0045739	biological_process	positive regulation of DNA repair
D	0050862	biological_process	positive regulation of T cell receptor signaling pathway
D	0051018	molecular_function	protein kinase A binding
D	0051092	biological_process	positive regulation of NF-kappaB transcription factor activity
D	0051225	biological_process	spindle assembly
D	0051301	biological_process	cell division
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051879	molecular_function	Hsp90 protein binding
D	0061481	biological_process	response to TNF agonist
D	0070062	cellular_component	extracellular exosome
D	0070181	molecular_function	small ribosomal subunit rRNA binding
D	0070301	biological_process	cellular response to hydrogen peroxide
D	0071159	cellular_component	NF-kappaB complex
D	0071356	biological_process	cellular response to tumor necrosis factor
D	0072686	cellular_component	mitotic spindle
D	0097100	molecular_function	supercoiled DNA binding
D	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D	0140297	molecular_function	DNA-binding transcription factor binding
D	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
D	1902231	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
D	1905053	biological_process	positive regulation of base-excision repair
D	1990904	cellular_component	ribonucleoprotein complex
D	2001235	biological_process	positive regulation of apoptotic signaling pathway
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0005925	cellular_component	focal adhesion
F	0006412	biological_process	translation
F	0006413	biological_process	translational initiation
F	0006450	biological_process	regulation of translational fidelity
F	0015935	cellular_component	small ribosomal subunit
F	0016020	cellular_component	membrane
F	0019843	molecular_function	rRNA binding
F	0022626	cellular_component	cytosolic ribosome
F	0022627	cellular_component	cytosolic small ribosomal subunit
F	0032040	cellular_component	small-subunit processome
F	0042274	biological_process	ribosomal small subunit biogenesis
F	0045202	cellular_component	synapse
F	0070062	cellular_component	extracellular exosome
F	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005730	cellular_component	nucleolus
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0005925	cellular_component	focal adhesion
K	0006412	biological_process	translation
K	0016020	cellular_component	membrane
K	0022626	cellular_component	cytosolic ribosome
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0045202	cellular_component	synapse
K	1990904	cellular_component	ribonucleoprotein complex
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005730	cellular_component	nucleolus
M	0005737	cellular_component	cytoplasm
M	0005794	cellular_component	Golgi apparatus
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0016020	cellular_component	membrane
M	0022626	cellular_component	cytosolic ribosome
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0032040	cellular_component	small-subunit processome
M	0042274	biological_process	ribosomal small subunit biogenesis
M	0090263	biological_process	positive regulation of canonical Wnt signaling pathway
M	1990145	biological_process	maintenance of translational fidelity
M	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0000056	biological_process	ribosomal small subunit export from nucleus
P	0001649	biological_process	osteoblast differentiation
P	0002181	biological_process	cytoplasmic translation
P	0003677	molecular_function	DNA binding
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0005925	cellular_component	focal adhesion
P	0006364	biological_process	rRNA processing
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0016020	cellular_component	membrane
P	0022626	cellular_component	cytosolic ribosome
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0042274	biological_process	ribosomal small subunit biogenesis
P	0045202	cellular_component	synapse
P	0097371	molecular_function	MDM2/MDM4 family protein binding
P	0097421	biological_process	liver regeneration
P	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
P	1990904	cellular_component	ribonucleoprotein complex
P	1990948	molecular_function	ubiquitin ligase inhibitor activity
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005730	cellular_component	nucleolus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0005925	cellular_component	focal adhesion
Q	0006364	biological_process	rRNA processing
Q	0006412	biological_process	translation
Q	0015935	cellular_component	small ribosomal subunit
Q	0016020	cellular_component	membrane
Q	0022626	cellular_component	cytosolic ribosome
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0032040	cellular_component	small-subunit processome
Q	0042274	biological_process	ribosomal small subunit biogenesis
Q	0045202	cellular_component	synapse
Q	0070062	cellular_component	extracellular exosome
Q	1990830	biological_process	cellular response to leukemia inhibitory factor
Q	1990904	cellular_component	ribonucleoprotein complex
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0005925	cellular_component	focal adhesion
R	0006364	biological_process	rRNA processing
R	0006412	biological_process	translation
R	0006413	biological_process	translational initiation
R	0016020	cellular_component	membrane
R	0022626	cellular_component	cytosolic ribosome
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0032040	cellular_component	small-subunit processome
R	0034101	biological_process	erythrocyte homeostasis
R	0042274	biological_process	ribosomal small subunit biogenesis
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003676	molecular_function	nucleic acid binding
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0005925	cellular_component	focal adhesion
S	0006412	biological_process	translation
S	0014069	cellular_component	postsynaptic density
S	0015935	cellular_component	small ribosomal subunit
S	0016020	cellular_component	membrane
S	0019843	molecular_function	rRNA binding
S	0022626	cellular_component	cytosolic ribosome
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	0045202	cellular_component	synapse
S	0070062	cellular_component	extracellular exosome
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
T	0002181	biological_process	cytoplasmic translation
T	0002548	biological_process	monocyte chemotaxis
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005730	cellular_component	nucleolus
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0005925	cellular_component	focal adhesion
T	0006364	biological_process	rRNA processing
T	0006412	biological_process	translation
T	0007000	biological_process	nucleolus organization
T	0014069	cellular_component	postsynaptic density
T	0016020	cellular_component	membrane
T	0017134	molecular_function	fibroblast growth factor binding
T	0019901	molecular_function	protein kinase binding
T	0022626	cellular_component	cytosolic ribosome
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0030218	biological_process	erythrocyte differentiation
T	0030490	biological_process	maturation of SSU-rRNA
T	0031640	biological_process	killing of cells of another organism
T	0032040	cellular_component	small-subunit processome
T	0042274	biological_process	ribosomal small subunit biogenesis
T	0042802	molecular_function	identical protein binding
T	0050829	biological_process	defense response to Gram-negative bacterium
T	0060265	biological_process	positive regulation of respiratory burst involved in inflammatory response
T	0060266	biological_process	negative regulation of respiratory burst involved in inflammatory response
T	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
T	0070062	cellular_component	extracellular exosome
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0015935	cellular_component	small ribosomal subunit
U	0016020	cellular_component	membrane
U	0022626	cellular_component	cytosolic ribosome
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	0045202	cellular_component	synapse
U	0070062	cellular_component	extracellular exosome
U	0097371	molecular_function	MDM2/MDM4 family protein binding
U	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
U	1990904	cellular_component	ribonucleoprotein complex
U	1990948	molecular_function	ubiquitin ligase inhibitor activity
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0014069	cellular_component	postsynaptic density
Z	0015935	cellular_component	small ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	0042274	biological_process	ribosomal small subunit biogenesis
Z	0045202	cellular_component	synapse
Z	0070062	cellular_component	extracellular exosome
Z	1990904	cellular_component	ribonucleoprotein complex
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005654	cellular_component	nucleoplasm
d	0005737	cellular_component	cytoplasm
d	0005783	cellular_component	endoplasmic reticulum
d	0005791	cellular_component	rough endoplasmic reticulum
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0005925	cellular_component	focal adhesion
d	0006412	biological_process	translation
d	0008270	molecular_function	zinc ion binding
d	0015935	cellular_component	small ribosomal subunit
d	0022626	cellular_component	cytosolic ribosome
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	0046872	molecular_function	metal ion binding
d	0070062	cellular_component	extracellular exosome
d	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
d	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
g	0001891	cellular_component	phagocytic cup
g	0001934	biological_process	positive regulation of protein phosphorylation
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0005080	molecular_function	protein kinase C binding
g	0005102	molecular_function	signaling receptor binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005737	cellular_component	cytoplasm
g	0005739	cellular_component	mitochondrion
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0005886	cellular_component	plasma membrane
g	0006412	biological_process	translation
g	0006417	biological_process	regulation of translation
g	0006915	biological_process	apoptotic process
g	0007369	biological_process	gastrulation
g	0008047	molecular_function	enzyme activator activity
g	0008200	molecular_function	ion channel inhibitor activity
g	0008656	molecular_function	cysteine-type endopeptidase activator activity involved in apoptotic process
g	0010629	biological_process	negative regulation of gene expression
g	0015935	cellular_component	small ribosomal subunit
g	0016020	cellular_component	membrane
g	0016567	biological_process	protein ubiquitination
g	0017148	biological_process	negative regulation of translation
g	0019899	molecular_function	enzyme binding
g	0019903	molecular_function	protein phosphatase binding
g	0022627	cellular_component	cytosolic small ribosomal subunit
g	0030178	biological_process	negative regulation of Wnt signaling pathway
g	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
g	0030292	molecular_function	protein tyrosine kinase inhibitor activity
g	0030308	biological_process	negative regulation of cell growth
g	0030332	molecular_function	cyclin binding
g	0030335	biological_process	positive regulation of cell migration
g	0030425	cellular_component	dendrite
g	0030496	cellular_component	midbody
g	0030971	molecular_function	receptor tyrosine kinase binding
g	0031334	biological_process	positive regulation of protein-containing complex assembly
g	0032091	biological_process	negative regulation of protein binding
g	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
g	0032880	biological_process	regulation of protein localization
g	0035591	molecular_function	signaling adaptor activity
g	0042169	molecular_function	SH2 domain binding
g	0042802	molecular_function	identical protein binding
g	0042803	molecular_function	protein homodimerization activity
g	0042995	cellular_component	cell projection
g	0042998	biological_process	positive regulation of Golgi to plasma membrane protein transport
g	0043005	cellular_component	neuron projection
g	0043022	molecular_function	ribosome binding
g	0043025	cellular_component	neuronal cell body
g	0043065	biological_process	positive regulation of apoptotic process
g	0043204	cellular_component	perikaryon
g	0043473	biological_process	pigmentation
g	0043547	biological_process	positive regulation of GTPase activity
g	0044297	cellular_component	cell body
g	0045182	molecular_function	translation regulator activity
g	0045296	molecular_function	cadherin binding
g	0045879	biological_process	negative regulation of smoothened signaling pathway
g	0048471	cellular_component	perinuclear region of cytoplasm
g	0048511	biological_process	rhythmic process
g	0050765	biological_process	negative regulation of phagocytosis
g	0051302	biological_process	regulation of cell division
g	0051434	molecular_function	BH3 domain binding
g	0051726	biological_process	regulation of cell cycle
g	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
g	0051901	biological_process	positive regulation of mitochondrial depolarization
g	0060090	molecular_function	molecular adaptor activity
g	0070062	cellular_component	extracellular exosome
g	0071333	biological_process	cellular response to glucose stimulus
g	0071363	biological_process	cellular response to growth factor stimulus
g	0072344	biological_process	rescue of stalled ribosome
g	0106070	biological_process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
g	1900102	biological_process	negative regulation of endoplasmic reticulum unfolded protein response
g	1903751	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
g	1990630	cellular_component	IRE1-RACK1-PP2A complex
g	1990904	cellular_component	ribonucleoprotein complex
g	2000114	biological_process	regulation of establishment of cell polarity
g	2000543	biological_process	positive regulation of gastrulation
g	2001125	biological_process	negative regulation of translational frameshifting
g	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG 2 2001

Chain	Residue
2	C1261
2	C1262
2	U1263
2	G1517

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MG 2 2002

Chain	Residue
2	G1387
2	A1388

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MG 2 2003

Chain	Residue
2	U1492
2	G1335
2	C1336
2	G1491

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MG 2 2004

Chain	Residue
2	G1603
2	G1604
2	G1605
2	G1606
2	MG2030

---

site_id	AC5
Number of Residues	1
Details	binding site for residue MG 2 2005

Chain	Residue
2	G1540

---

site_id	AC6
Number of Residues	5
Details	binding site for residue MG 2 2006

Chain	Residue
2	C1655
2	G1656
2	U1667
2	U1668
2	G1669

---

site_id	AC7
Number of Residues	1
Details	binding site for residue MG 2 2007

Chain	Residue
2	U1519

---

site_id	AC8
Number of Residues	2
Details	binding site for residue MG 2 2008

Chain	Residue
2	G1226
2	G1227

---

site_id	AC9
Number of Residues	1
Details	binding site for residue MG 2 2009

Chain	Residue
2	C1262

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MG 2 2010

Chain	Residue
2	A1259
2	A1260

---

site_id	AD2
Number of Residues	1
Details	binding site for residue MG 2 2011

Chain	Residue
2	A1258

---

site_id	AD3
Number of Residues	4
Details	binding site for residue MG 2 2012

Chain	Residue
2	A1537
2	G1604
2	G1605
2	MG2042

---

site_id	AD4
Number of Residues	1
Details	binding site for residue MG 2 2013

Chain	Residue
2	U1653

---

site_id	AD5
Number of Residues	2
Details	binding site for residue MG 2 2014

Chain	Residue
2	G1510
2	U1511

---

site_id	AD6
Number of Residues	1
Details	binding site for residue MG 2 2015

Chain	Residue
2	C1337

---

site_id	AD7
Number of Residues	3
Details	binding site for residue MG 2 2016

Chain	Residue
2	C1331
2	G1490
2	G1491

---

site_id	AD8
Number of Residues	2
Details	binding site for residue MG 2 2017

Chain	Residue
2	G1385
2	G1387

---

site_id	AD9
Number of Residues	3
Details	binding site for residue MG 2 2018

Chain	Residue
2	G1330
2	G1334
2	U1496

---

site_id	AE1
Number of Residues	1
Details	binding site for residue MG 2 2019

Chain	Residue
2	C1219

---

site_id	AE2
Number of Residues	2
Details	binding site for residue MG 2 2020

Chain	Residue
2	A1217
2	U1643

---

site_id	AE3
Number of Residues	2
Details	binding site for residue MG 2 2021

Chain	Residue
2	U1442
2	C1443

---

site_id	AE4
Number of Residues	3
Details	binding site for residue MG 2 2022

Chain	Residue
2	U1530
2	G1606
T	GLY86

---

site_id	AE5
Number of Residues	2
Details	binding site for residue MG 2 2023

Chain	Residue
2	A1253
2	C1254

---

site_id	AE6
Number of Residues	2
Details	binding site for residue MG 2 2024

Chain	Residue
2	G1224
2	U1225

---

site_id	AE7
Number of Residues	2
Details	binding site for residue MG 2 2025

Chain	Residue
2	C1331
2	G1490

---

site_id	AE8
Number of Residues	2
Details	binding site for residue MG 2 2026

Chain	Residue
2	U1659
2	A1664

---

site_id	AE9
Number of Residues	2
Details	binding site for residue MG 2 2028

Chain	Residue
2	U1326
2	U1494

---

site_id	AF1
Number of Residues	1
Details	binding site for residue MG 2 2029

Chain	Residue
2	U1360

---

site_id	AF2
Number of Residues	4
Details	binding site for residue MG 2 2030

Chain	Residue
2	U1602
2	G1603
2	G1605
2	MG2004

---

site_id	AF3
Number of Residues	3
Details	binding site for residue MG 2 2031

Chain	Residue
2	C1493
2	U1494
2	U1499

---

site_id	AF4
Number of Residues	2
Details	binding site for residue MG 2 2033

Chain	Residue
2	C1538
2	U1539

---

site_id	AF5
Number of Residues	1
Details	binding site for residue MG 2 2034

Chain	Residue
2	U1340

---

site_id	AF6
Number of Residues	4
Details	binding site for residue MG 2 2035

Chain	Residue
2	U1225
2	G1226
2	G1227
2	G1638

---

site_id	AF7
Number of Residues	1
Details	binding site for residue MG 2 2036

Chain	Residue
2	U1672

---

site_id	AF8
Number of Residues	3
Details	binding site for residue MG 2 2037

Chain	Residue
2	G1255
2	G1257
2	U1494

---

site_id	AF9
Number of Residues	2
Details	binding site for residue MG 2 2039

Chain	Residue
2	C1273
2	C1316

---

site_id	AG1
Number of Residues	2
Details	binding site for residue MG 2 2040

Chain	Residue
2	G1536
2	C1591

---

site_id	AG2
Number of Residues	5
Details	binding site for residue MG 2 2041

Chain	Residue
2	G1328
2	U1329
2	C1493
2	G1500
2	C1501

---

site_id	AG3
Number of Residues	3
Details	binding site for residue MG 2 2042

Chain	Residue
2	G1604
2	G1605
2	MG2012

---

site_id	AG4
Number of Residues	3
Details	binding site for residue MG 2 2043

Chain	Residue
2	C1682
2	U1685
2	G1686

---

site_id	AG5
Number of Residues	3
Details	binding site for residue MG 2 2044

Chain	Residue
2	U1519
2	A1623
S	GLY133

---

site_id	AG6
Number of Residues	4
Details	binding site for residue MG 2 2045

Chain	Residue
2	G1298
2	A1299
2	C1513
2	G1514

---

site_id	AG7
Number of Residues	5
Details	binding site for residue MG 2 2046

Chain	Residue
2	G1233
2	C1234
2	G1245
2	C1254
2	G1255

---

site_id	AG8
Number of Residues	3
Details	binding site for residue MG 2 2047

Chain	Residue
2	C1234
2	C1252
2	C1525

---

site_id	AG9
Number of Residues	1
Details	binding site for residue MG 2 2048

Chain	Residue
2	G1528

---

site_id	AH1
Number of Residues	3
Details	binding site for residue MG 2 2049

Chain	Residue
2	U1367
2	U1368
2	U1372

---

site_id	AH2
Number of Residues	4
Details	binding site for residue MG 2 2050

Chain	Residue
2	G1528
2	C1529
2	C1666
2	U1667

---

site_id	AH3
Number of Residues	5
Details	binding site for residue MG 2 2051

Chain	Residue
2	U1243
2	U1244
2	A1265
2	U1494
f	LYS78

---

site_id	AH4
Number of Residues	3
Details	binding site for residue MG 2 2052

Chain	Residue
2	G1517
2	C1518
2	U1622

---

site_id	AH5
Number of Residues	3
Details	binding site for residue MG 2 2053

Chain	Residue
2	C1261
2	G1514
2	G1515

---

site_id	AH6
Number of Residues	5
Details	binding site for residue MG F 301

Chain	Residue
2	C1534
2	U1535
F	ALA162
F	ASN165
F	LYS167

---

site_id	AH7
Number of Residues	3
Details	binding site for residue MG S 201

Chain	Residue
2	C1521
S	THR136
S	THR139

---

site_id	AH8
Number of Residues	4
Details	binding site for residue MG S 202

Chain	Residue
2	U1631
S	THR31
S	ILE33
S	VAL36

---

site_id	AH9
Number of Residues	3
Details	binding site for residue MG T 201

Chain	Residue
2	A1589
T	ILE78
T	GLY80

---

site_id	AI1
Number of Residues	4
Details	binding site for residue ZN d 201

Chain	Residue
d	CYS21
d	CYS24
d	CYS39
d	CYS42

---

site_id	AI2
Number of Residues	5
Details	binding site for residue ZN f 500

Chain	Residue
f	CYS121
f	SER123
f	CYS126
f	CYS141
f	CYS144

---

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
F	GLU70-ALA96

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
P	ASN98-THR122

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
Q	GLY74-LEU92

---

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
U	ALA43-THR58

---

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
d	ARG22-ARG44

---

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
D	ALA147-GLY183

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
T	PRO89-GLU108

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
S	ARG121-GLN134

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
g	ALA78-LEU92
g	ILE120-THR134
g	ILE165-LEU179
g	CYS207-LEU221

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
R	ILE41-HIS56

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
c	GLU60-LEU68

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
M	ALA17-ILE35

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	23
Details	ZN_FING: C4-type

Chain	Residue	Details
f	CYS121-CYS144
T	LYS111

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
f	LYS104
f	LYS113

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36638793

Chain	Residue	Details
f	LYS107
g	THR10
g	THR96

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:32129764, ECO:0000269|PubMed:36638793

Chain	Residue	Details
g	TYR52
f	LYS113
S	LYS106

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
g	LYS130
K	LYS139

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P68040

Chain	Residue	Details
g	LYS183
D	ARG65
D	ARG67

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:11279199

Chain	Residue	Details
g	TYR228
U	LYS8

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphoserine; by viral VacV B1 kinase => ECO:0000269|PubMed:28636603, ECO:0007744|PubMed:23186163

Chain	Residue	Details
g	SER276

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by viral VacV B1 kinase => ECO:0000269|PubMed:28636603

Chain	Residue	Details
g	THR277

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: Phosphoserine; by viral VacV B1 kinase => ECO:0000269|PubMed:28636603

Chain	Residue	Details
g	SER278
g	SER279

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by CDK1 and PKC/PRKCD => ECO:0000269|PubMed:19059439, ECO:0000269|PubMed:21871177, ECO:0000269|Ref.12, ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
D	THR221

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16807684

Chain	Residue	Details
D	SER224

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:24275569

Chain	Residue	Details
D	THR242

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)

Chain	Residue	Details
D	LYS90
D	LYS202

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:28112733

Chain	Residue	Details
D	LYS230

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:28065601, ECO:0000269|PubMed:28132843, ECO:0000269|PubMed:31981475, ECO:0000269|PubMed:32011234, ECO:0000269|PubMed:34348161, ECO:0000269|PubMed:34469731

Chain	Residue	Details
D	LYS214

---