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6IA0
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Human telomeric G-quadruplex with 8-oxo-G substitution in the central G-quartet
分子名称: hTel-oxoG10
著者Bielskute, S, Plavec, J, Podbevsek, P.
登録日2018-11-26
公開日2019-01-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Impact of Oxidative Lesions on the Human Telomeric G-Quadruplex.
J. Am. Chem. Soc., 141, 2019
6IA4
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Human telomeric G-quadruplex with 8-oxo-G substitution in the outer G-quartet
分子名称: hTel-oxoG21
著者Bielskute, S, Plavec, J, Podbevsek, P.
登録日2018-11-26
公開日2019-01-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Impact of Oxidative Lesions on the Human Telomeric G-Quadruplex.
J. Am. Chem. Soc., 141, 2019
6JCE
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NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes
分子名称: 29-mer DNA
著者Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T.
登録日2019-01-28
公開日2019-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes.
Nucleic Acids Res., 47, 2019
8JIH
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human telomere two-quartet G-quadruplex at pH 5.0
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3')
著者Wang, B, Galer, P, Plavec, J.
登録日2023-05-26
公開日2024-04-03
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Unveiling the structural mechanism of a G-quadruplex pH-Driven switch.
Biochimie, 214, 2023
8JIC
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human telomere two-quartet G-quadruplex at pH 7.0
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3')
著者Wang, B, Galer, P, Plavec, J.
登録日2023-05-26
公開日2024-04-03
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Unveiling the structural mechanism of a G-quadruplex pH-Driven switch.
Biochimie, 214, 2023
5J6U
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DIY G-Quadruplexes: Solution Structure of d(GGGGTTTGGGGTTTTGGGGAAGGGG) in sodium
分子名称: DNA (25-MER)
著者Dvorkin, S.A, Karsisiotis, A.I, Webba da Silva, M.
登録日2016-04-05
公開日2017-05-10
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Encoding canonical DNA quadruplex structure.
Sci Adv, 4, 2018
8X1V
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NMR structure of a bimolecular parallel G-quadruplex formed by AAGGG repeats from pathogenic RFC1 gene
分子名称: DNA (5'-D(*AP*AP*GP*GP*GP*AP*AP*GP*GP*GP*AP*A)-3')
著者Wang, Y, Guo, P, Han, D.
登録日2023-11-08
公開日2024-01-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS.
Nucleic Acids Res., 52, 2024
6CRM
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BU of 6crm by Molmil
Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex
分子名称: DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3'), RecQ, ZINC ION
著者Voter, A.F, Keck, J.L.
登録日2018-03-19
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.19286251 Å)
主引用文献A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases.
Nat Commun, 9, 2018
5J05
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DIY G-Quadruplexes: Solution structure of d(GGGTTTGGGTTTTGGGAGGG) in sodium
分子名称: DNA (5'-D(*GP*GP*GP*TP*TP*TP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*AP*GP*GP*G)-3')
著者Dvorkin, S.A, Karsisiotis, A.I, Webba da Silva, M.
登録日2016-03-27
公開日2017-04-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Encoding canonical DNA quadruplex structure.
Sci Adv, 4, 2018
5MVB
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Solution structure of a human G-Quadruplex hybrid-2 form in complex with a Gold-ligand.
分子名称: DNA (26-MER), POTASSIUM ION, bis(m2-Oxo)-bis(2-methyl-2,2'-bipyridine)-di-gold(iii)
著者Wirmer-Bartoschek, J, Jonker, H.R.A, Bendel, L.E, Gruen, T, Bazzicalupi, C, Messori, L, Gratteri, P, Schwalbe, H.
登録日2017-01-16
公開日2017-05-31
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding.
Angew. Chem. Int. Ed. Engl., 56, 2017
6T51
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NMR structure of KRAS22RT G-quadruplex forming within KRAS promoter region at physological temperature
分子名称: KRAS22RT, POTASSIUM ION
著者Marquevielle, J, Salgado, G.
登録日2019-10-15
公開日2019-10-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H,13C, and15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.
Biomol.Nmr Assign., 12, 2018
7NTU
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BU of 7ntu by Molmil
X-ray structure of the complex between human alpha thrombin and two duplex/quadruplex aptamers: NU172 and HD22_27mer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, HD22_27mer, ...
著者Troisi, R, Santamaria, A, Sica, F.
登録日2021-03-10
公開日2021-04-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human alpha-thrombin.
Int.J.Biol.Macromol., 181, 2021
1MF5
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GCATGCT Quadruplex
分子名称: 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT HEXAMMINE(III)
著者Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Cardin, C.J.
登録日2002-08-09
公開日2003-02-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Crystal structure of the complementary quadruplex formed by d(GCATGCT) at atomic resolution
Nucleic Acids Res., 31, 2003
7Z9L
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BU of 7z9l by Molmil
Phen-DC3 intercalation causes hybrid-to-antiparallel transformation of human telomeric DNA G-quadruplex
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
著者Ghosh, A, Trajkovski, M, Teulade-Fichou, M.P, Gabelica, V, Plavec, J.
登録日2022-03-21
公開日2022-08-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Phen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation.
Angew.Chem.Int.Ed.Engl., 61, 2022
7V6V
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trimolecular G-quadruplexes consists of a hairpin motif and two short chains
分子名称: DNA (5'-D(*CP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*GP*GP*GP*A)-3')
著者Zhang, N, Jing, H.T, Hu, W.X.
登録日2021-08-20
公開日2023-02-08
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Conversion to Trimolecular G-Quadruplex by Spontaneous Hoogsteen Pairing-Based Strand Displacement Reaction between Bimolecular G-Quadruplex and Double G-Rich Probes.
J.Am.Chem.Soc., 2023
7QVQ
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Human telomeric DNA G-quadruplex of a gold(III) complex containing the 2,4,6-tris (2-pyrimidyl)-1,3,5-triazine ligand
分子名称: 2,4,6-tris (2-pyrimidyl)-1,3,5-triazine gold(III) complex, POTASSIUM ION, human telomeric DNA
著者Bazzicalupi, C, Ryde, U, Gratteri, P, Bergmann, J.
登録日2022-01-23
公開日2022-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis.
Int J Mol Sci, 23, 2022
8EBO
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Homopurine parallel G-quadruplex from human chromosome 7 stabilized by K+ ions
分子名称: COBALT (III) ION, DNA (5'-D(*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*A)-3'), N-METHYLMESOPORPHYRIN, ...
著者Chen, E.V, Yatsunyk, L.A.
登録日2022-08-31
公開日2022-12-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad.
Bioorg.Med.Chem., 77, 2022
8EDP
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Crystal structure of a three-tetrad, parallel, and K+ stabilized homopurine G-quadruplex from human chromosome 7
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN, ...
著者Ye, M, Yatsunyk, L.A.
登録日2022-09-05
公開日2022-12-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad.
Bioorg.Med.Chem., 77, 2022
4RJ1
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BU of 4rj1 by Molmil
Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions
分子名称: CALCIUM ION, RNA (5'-R(*UP*GP*GP*GP*GP*U)-3'), SODIUM ION, ...
著者Fyfe, A.C, Dunten, P.W, Scott, W.G.
登録日2014-10-08
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.92 Å)
主引用文献Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
J.Mol.Biol., 427, 2015
4RNE
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BU of 4rne by Molmil
Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions
分子名称: CALCIUM ION, RNA (5'-R(*UP*GP*GP*GP*GP*U)-3'), SODIUM ION, ...
著者Fyfe, A.C, Dunten, P.W, Scott, W.G.
登録日2014-10-24
公開日2014-11-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.01 Å)
主引用文献Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
J.Mol.Biol., 427, 2015
8JFQ
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Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop
分子名称: 26mer-DNA
著者Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y.
登録日2023-05-18
公開日2023-08-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J.Am.Chem.Soc., 145, 2023
5NYS
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M2 G-quadruplex dilute solution
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N.
登録日2017-05-11
公開日2018-04-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
5NYU
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M2 G-quadruplex 10 wt% PEG8000
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N.
登録日2017-05-11
公開日2018-04-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
5NYT
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M2 G-quadruplex 20 wt% ethylene glycol
分子名称: DNA (5'-D(*TP*AP*GP*GP*GP*AP*CP*GP*GP*GP*CP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Trajkovski, M, Plavec, J, Endoh, T, Tateishi-Karimata, H, Sugimoto, N.
登録日2017-05-11
公開日2018-04-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Pursuing origins of (poly)ethylene glycol-induced G-quadruplex structural modulations.
Nucleic Acids Res., 46, 2018
4RKV
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BU of 4rkv by Molmil
Structural variations and solvent structure of UGGGGU quadruplexes stabilized by Sr2+ ions
分子名称: CALCIUM ION, RNA (5'-R(*UP*GP*GP*GP*GP*U)-3'), SODIUM ION, ...
著者Fyfe, A.C, Dunten, P.W, Scott, W.G.
登録日2014-10-14
公開日2014-11-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.88 Å)
主引用文献Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
J.Mol.Biol., 427, 2015

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