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8EBO

Homopurine parallel G-quadruplex from human chromosome 7 stabilized by K+ ions

Summary for 8EBO
Entry DOI10.2210/pdb8ebo/pdb
DescriptorDNA (5'-D(*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*A)-3'), N-METHYLMESOPORPHYRIN, POTASSIUM ION, ... (5 entities in total)
Functional Keywordsg-quadruplex, parallel, propeller loops, dna
Biological sourceHomo sapiens
Total number of polymer chains1
Total formula weight7826.52
Authors
Chen, E.V.,Yatsunyk, L.A. (deposition date: 2022-08-31, release date: 2022-12-28, Last modification date: 2023-10-25)
Primary citationYe, M.,Chen, E.V.,Pfeil, S.H.,Martin, K.N.,Atrafi, T.,Yun, S.,Martinez, Z.,Yatsunyk, L.A.
Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad.
Bioorg.Med.Chem., 77:117112-117112, 2022
Cited by
PubMed: 36508994
DOI: 10.1016/j.bmc.2022.117112
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.98 Å)
Structure validation

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