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PDB: 338 件

8ITP
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Crystal structure of USP47 catalytic domain complex with ubiquitin
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION
著者Kim, E.E, Shin, S.C.
登録日2023-03-22
公開日2024-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional characterization of USP47 reveals a hot spot for inhibitor design.
Commun Biol, 6, 2023
3N30
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BU of 3n30 by Molmil
Crystal Structure of cubic Zn3-hUb (human ubiquitin) adduct
分子名称: Ubiquitin, ZINC ION
著者Siliqi, D, Caliandro, R, Arnesano, F, Natile, G, Falini, G, Fermani, S, Belviso, B.D.
登録日2010-05-19
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic analysis of metal-ion binding to human ubiquitin.
Chemistry, 17, 2011
3PHD
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BU of 3phd by Molmil
Crystal structure of human HDAC6 in complex with ubiquitin
分子名称: Histone deacetylase 6, Polyubiquitin, ZINC ION
著者Dong, A, Qui, W, Ravichandran, M, Schuetz, A, Loppnau, P, Li, F, Mackenzie, F, Kozieradzki, I, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2010-11-03
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini.
J.Biol.Chem., 287, 2012
3EEC
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BU of 3eec by Molmil
X-ray structure of human ubiquitin Cd(II) adduct
分子名称: CADMIUM ION, Ubiquitin
著者Falini, G, Fermani, S, Tosi, G, Arnesano, F, Natile, G.
登録日2008-09-04
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural probing of Zn(II), Cd(II) and Hg(II) binding to human ubiquitin.
Chem.Commun.(Camb.), 45, 2008
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
分子名称: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
著者Ren, W, Song, J.
登録日2019-08-01
公開日2020-07-15
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6HEK
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BU of 6hek by Molmil
Structure of human USP28 bound to Ubiquitin-PA
分子名称: CHLORIDE ION, Polyubiquitin-B, TETRAETHYLENE GLYCOL, ...
著者Gersch, M, Komander, D.
登録日2018-08-20
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
8HQY
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BU of 8hqy by Molmil
Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom
分子名称: DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ...
著者Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L.
登録日2022-12-14
公開日2023-09-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
8GRM
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BU of 8grm by Molmil
Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome
分子名称: COMMD3 protein, DNA (144-MER), DNA (145-MER), ...
著者Ai, H.S, Zebin, T, Zhihend, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L.
登録日2022-09-02
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
8WG5
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BU of 8wg5 by Molmil
Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L.
登録日2023-09-20
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome
To Be Published
8G6H
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BU of 8g6h by Molmil
H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 6
分子名称: 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-02-15
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
7MC9
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BU of 7mc9 by Molmil
X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA
分子名称: 3C-like proteinase, Ubiquitin, ZINC ION, ...
著者Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2021-04-01
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.099 Å)
主引用文献Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin
Acta Cryst. D, 77, 2021
7E8I
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BU of 7e8i by Molmil
Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin
分子名称: BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ...
著者Dai, Y, Dai, L, Zhou, Z.
登録日2021-03-01
公開日2021-06-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Mol.Cell, 81, 2021
7W38
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BU of 7w38 by Molmil
Structure of USP14-bound human 26S proteasome in state EA2.0_UBL
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
3JW0
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BU of 3jw0 by Molmil
E2~Ubiquitin-HECT
分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Kamadurai, H.B, Schulman, B.A.
登録日2009-09-17
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex.
Mol.Cell, 36, 2009
5YIK
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BU of 5yik by Molmil
Structure of a Legionella effector with its substrate
分子名称: SdeA, ubiquitin
著者Feng, Y, Dong, Y, Liu, Z.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
7W3U
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BU of 7w3u by Molmil
USP34 catalytic domain in complex with UbPA
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 34, ZINC ION, ...
著者Xu, G.L, Ming, Z.H.
登録日2021-11-26
公開日2022-06-01
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Structural Insights into the Catalytic Mechanism and Ubiquitin Recognition of USP34.
J.Mol.Biol., 434, 2022
5O44
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BU of 5o44 by Molmil
Crystal structure of unbranched mixed tri-Ubiquitin chain containing K48 and K63 linkages.
分子名称: MAGNESIUM ION, Polyubiquitin-B, SULFATE ION, ...
著者Padala, P, Isupov, M.N, Wiener, R.
登録日2017-05-26
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献The Crystal Structure and Conformations of an Unbranched Mixed Tri-Ubiquitin Chain Containing K48 and K63 Linkages.
J. Mol. Biol., 429, 2017
5LN1
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BU of 5ln1 by Molmil
STRUCTURE OF UBIQUITYLATED-RPN10 FROM YEAST;
分子名称: 26S proteasome regulatory subunit RPN10, Polyubiquitin-B
著者Keren-Kaplan, T, Attali, I, Levin-Kravets, O, Prag, G.
登録日2016-08-02
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.
Nat Commun, 7, 2016
4WUR
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BU of 4wur by Molmil
The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
分子名称: ISOPROPYL ALCOHOL, Papain-like protease, Polyubiquitin-B, ...
著者Lei, J, Hilgenfeld, R.
登録日2014-11-03
公開日2014-11-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin.
Virol Sin, 31, 2016
5YIJ
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BU of 5yij by Molmil
Structure of a Legionella effector with substrates
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SdeA, Ubiquitin
著者Feng, Y, Mu, Y, Wang, H.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
6MSD
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BU of 6msd by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
5ZBU
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BU of 5zbu by Molmil
Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub
分子名称: E3 ubiquitin-protein ligase RNF13, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Datta, A.B, Sarkar, S.
登録日2018-02-12
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of PA-TM-RING E3 ligase RNF13 RING domain in complex with E2~Ub
To Be Published
7DNI
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BU of 7dni by Molmil
MDA5 CARDs-MAVS CARD polyUb complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Mitochondrial antiviral-signaling protein, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
7AY2
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BU of 7ay2 by Molmil
Crystal structure of truncated USP1-UAF1 reacted with ubiquitin-prg
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 1, WD repeat-containing protein 48, ...
著者Arkinson, C, Rennie, M.L, Walden, H.
登録日2020-11-10
公開日2021-03-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of FANCD2 deubiquitination by USP1-UAF1.
Nat.Struct.Mol.Biol., 28, 2021
7W3H
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BU of 7w3h by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022

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