8HQY

Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom

Summary for 8HQY

Entry DOI	10.2210/pdb8hqy/pdb
EMDB information	34954
Descriptor	Histone H3, DNA (136-MER), Histone H4 (Fragment), ... (10 entities in total)
Functional Keywords	ssx1, h2ak119ub nucleosome, synovial sarcoma, ssbaf, reader protein, structural protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	180393.42
Authors	Zebin, T.,Ai, H.S.,Ziyu, X.,GuoChao, C.,Man, P.,Liu, L. (deposition date: 2022-12-14, release date: 2023-09-27, Last modification date: 2024-03-06)
Primary citation	Tong, Z.,Ai, H.,Xu, Z.,He, K.,Chu, G.C.,Shi, Q.,Deng, Z.,Xue, Q.,Sun, M.,Du, Y.,Liang, L.,Li, J.B.,Pan, M.,Liu, L. Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31:300-310, 2024 Cited by PubMed: 38177667 DOI: 10.1038/s41594-023-01141-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.05 Å)

Structure validation