8HQY

Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3	polymer	97	11401.3	2	UniProt (A0A653DHJ5) Pfam (PF00125) UniProt (by SIFTS) (Q71DI3) In PDB	Homo sapiens (human)
2	B	Histone H4 (Fragment)	polymer	83	9509.2	1	UniProt (A0A093PN76) Pfam (PF15511) UniProt (by SIFTS) (P62805) In PDB	Homo sapiens (human)
3	C	Histone H2A type 1-B/E	polymer	107	11740.7	1	UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB	Homo sapiens (human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
4	D, H	Histone H2B type 1-K	polymer	91	10076.5	2	UniProt (O60814) Pfam (PF00125) In PDB	Homo sapiens (human)	H2B K,HIRA-interacting protein 1
5	F	Histone H4	polymer	81	9222.8	1	UniProt (A0A8C2GGI7) Pfam (PF15511) UniProt (by SIFTS) (P62805) In PDB	Homo sapiens (human)
6	G	Histone H2A type 1-B/E	polymer	106	11637.6	1	UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB	Homo sapiens (human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
7	S	Protein SSX2	polymer	23	2912.3	1	UniProt (Q16385) Pfam (PF09514) In PDB	Homo sapiens (human)	Cancer/testis antigen 5.2,CT5.2,Synovial sarcoma,X breakpoint 2,Tumor antigen HOM-MEL-40
8	U	Polyubiquitin-B (Fragment)	polymer	74	8462.7	1	UniProt (J3QS39) Pfam (PF00240) UniProt (by SIFTS) (P0CG47) In PDB	Homo sapiens (human)
9	I	DNA (137-MER)	polymer	136	41800.6	1		Homo sapiens
10	J	DNA (136-MER)	polymer	136	42151.8	1		Homo sapiens

Sequence modifications

C: 13 - 118 (UniProt: P04908)

PDB	External Database	Details
Cys 119	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	180393.4
All*	Total formula weight	180393.4

*Water molecules are not included.