8ITP

Crystal structure of USP47 catalytic domain complex with ubiquitin

Summary for 8ITP

• Entry DOI: 10.2210/pdb8itp/pdb
• Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 47, ZINC ION (3 entities in total)
• Functional Keywords: ubiquitin specific protease, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 132420.25

Authors

Kim, E.E.,Shin, S.C. (deposition date: 2023-03-22, release date: 2024-03-27)

• Primary citation: Shin, S.C.,Park, J.,Kim, K.H.,Yoon, J.M.,Cho, J.,Ha, B.H.,Oh, Y.,Choo, H.,Song, E.J.,Kim, E.E.; Structural and functional characterization of USP47 reveals a hot spot for inhibitor design; Commun Biol, 6:970-, 2023; DOI: 10.1038/s42003-023-05345-5

Experimental method

X-RAY DIFFRACTION (3 Å)