3PHD
Crystal structure of human HDAC6 in complex with ubiquitin
Summary for 3PHD
Entry DOI | 10.2210/pdb3phd/pdb |
Related | 2ZNV 3C5K 3GV4 3NHE |
Descriptor | Histone deacetylase 6, Polyubiquitin, ZINC ION, ... (4 entities in total) |
Functional Keywords | hdac6, ubiquitin, structural genomics, structural genomics consortium, sgc, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9UBN7 |
Total number of polymer chains | 8 |
Total formula weight | 83187.19 |
Authors | Dong, A.,Qui, W.,Ravichandran, M.,Schuetz, A.,Loppnau, P.,Li, F.,Mackenzie, F.,Kozieradzki, I.,Ouyang, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-11-03, release date: 2011-02-23, Last modification date: 2023-09-06) |
Primary citation | Ouyang, H.,Ali, Y.O.,Ravichandran, M.,Dong, A.,Qiu, W.,Mackenzie, F.,Dhe-Paganon, S.,Arrowsmith, C.H.,Zhai, R.G. Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini. J.Biol.Chem., 287:2317-2327, 2012 Cited by PubMed: 22069321DOI: 10.1074/jbc.M111.273730 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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