2ZNV

Crystal structure of human AMSH-LP DUB domain in complex with Lys63-linked ubiquitin dimer

Summary for 2ZNV

• Entry DOI: 10.2210/pdb2znv/pdb
• Related: 2ZNR
• Descriptor: AMSH-like protease, Ubiquitin, ZINC ION, ... (6 entities in total)
• Functional Keywords: protein complex, metal binding protein, alternative splicing, hydrolase, metal-binding, metalloprotease, protease, ubl conjugation pathway, zinc, cytoplasm, nucleus, phosphoprotein, hydrolase-signaling protein complex, hydrolase/signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 74743.01

Authors

Sato, Y.,Azusa, Y.,Yamagata, A.,Mimura, H.,Wang, X.,Yamashita, M.,Ookata, K.,Nureki, O.,Iwai, K.,Komada, M.,Fukai, S. (deposition date: 2008-05-01, release date: 2008-09-02, Last modification date: 2023-11-01)

• Primary citation: Sato, Y.,Yoshikawa, A.,Yamagata, A.,Mimura, H.,Yamashita, M.,Ookata, K.,Nureki, O.,Iwai, K.,Komada, M.,Fukai, S.; Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains; Nature, 455:358-362, 2008; PubMed: 18758443; DOI: 10.1038/nature07254

Experimental method

X-RAY DIFFRACTION (1.6 Å)