Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| A | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| A | 0070536 | biological_process | protein K63-linked deubiquitination |
| A | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0008237 | molecular_function | metallopeptidase activity |
| D | 0016579 | biological_process | protein deubiquitination |
| D | 0061578 | molecular_function | K63-linked deubiquitinase activity |
| D | 0070536 | biological_process | protein K63-linked deubiquitination |
| D | 0140492 | molecular_function | metal-dependent deubiquitinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | HIS362 |
| A | CYS402 |
| A | HIS408 |
| A | HIS410 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 2 |
| Chain | Residue |
| D | HIS362 |
| D | CYS402 |
| D | HIS408 |
| D | HIS410 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| A | SER366 |
| A | SER400 |
| A | HOH528 |
| B | GLY35 |
| B | PRO37 |
| B | GLN40 |
| A | HIS362 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 77 |
| Chain | Residue |
| A | HOH439 |
| B | THR7 |
| B | LEU8 |
| B | LEU69 |
| B | VAL70 |
| B | LEU71 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 3 |
| Chain | Residue |
| C | ASP32 |
| D | VAL359 |
| D | LYS405 |
| D | GLY406 |
| D | PHE407 |
| D | HOH610 |
| E | ARG74 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 | |
| C | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Interacts with activating enzyme |
| Chain | Residue | Details |
| C | ARG54 | |
| C | ARG72 | |
| F | ARG54 | |
| F | ARG72 | |
| D | HIS349 | |
| D | ASP360 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Essential for function |
| Chain | Residue | Details |
| C | HIS68 | |
| F | HIS68 | |
| A | HIS408 | |
| A | HIS410 | |
| D | HIS362 | |
| D | CYS402 | |
| D | HIS408 | |
| D | HIS410 | |
| Chain | Residue | Details |
| C | SER65 | |
| F | SER65 | |
| Chain | Residue | Details |
| C | GLY76 | |
| F | GLY76 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P0CG48 |
| Chain | Residue | Details |
| C | LYS6 | |
| F | LYS27 | |
| F | LYS29 | |
| F | LYS33 | |
| F | LYS48 | |
| F | LYS63 | |
| C | LYS11 | |
| C | LYS27 | |
| C | LYS29 | |
| C | LYS33 | |
| C | LYS48 | |
| C | LYS63 | |
| F | LYS6 | |
| F | LYS11 | |
| Chain | Residue | Details |
| C | GLY76 | |
| F | GLY76 | |
