7W3H
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14
This is a non-PDB format compatible entry.
Summary for 7W3H
Entry DOI | 10.2210/pdb7w3h/pdb |
EMDB information | 32280 |
Descriptor | 26S protease regulatory subunit 7, Proteasome subunit alpha type-7, Proteasome subunit alpha type-5, ... (39 entities in total) |
Functional Keywords | proteasome, aaa-atpase, deubiquitinase, usp14, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 49 |
Total formula weight | 1735619.73 |
Authors | |
Primary citation | Zhang, S.,Zou, S.,Yin, D.,Zhao, L.,Finley, D.,Wu, Z.,Mao, Y. USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605:567-574, 2022 Cited by PubMed: 35477760DOI: 10.1038/s41586-022-04671-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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