8GRM

Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome

Summary for 8GRM

• Entry DOI: 10.2210/pdb8grm/pdb
• EMDB information: 34207
• Descriptor: Histone H3, Ubiquitin, UbcH5b, ... (12 entities in total)
• Functional Keywords: prc1, ring1b, bmi1, h2ak119, h2ak119-ubch5c-ub, nucleosome, nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 225887.28

Authors

Ai, H.S.,Zebin, T.,Zhihend, D.,Jiakun, T.,Liying, Z.,Jia-Bin, L.,Man, P.,Liu, L. (deposition date: 2022-09-02, release date: 2023-04-12)

• Primary citation: Ai, H.S.,Tong, Z.,Deng, Z.,Tian, J.,Zhang, L.,Sun, M.,Du, Y.,Xu, Z.,Shi, Q.,Liang, L.,Zheng, Q.,Li, J.B.,Pan, M.,Liu, L.; Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.; Chem, 2023; DOI: 10.1016/j.chempr.2023.01.012

Experimental method

ELECTRON MICROSCOPY (3.05 Å)