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PDB: 338 件

2JF5
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BU of 2jf5 by Molmil
crystal structure of Lys63-linked di-ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ...
著者Komander, D, Odenwaelder, P, Barford, D.
登録日2007-01-26
公開日2008-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains.
Embo Rep., 10, 2009
5NL5
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BU of 5nl5 by Molmil
Crystal structure of Zn1.7-E16V human ubiquitin (hUb) mutant adduct, from a solution 70 mM zinc acetate/1.3 mM E16V hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Polyubiquitin-B, ...
著者Fermani, S, Falini, G.
登録日2017-04-04
公開日2017-04-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium.
Chemistry, 24, 2018
3HM3
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BU of 3hm3 by Molmil
The Structure and conformation of Lys-63 linked tetra-ubiquitin
分子名称: Ubiquitin, ZINC ION
著者Datta, A.B, Hura, G.L, Wolberger, C.
登録日2009-05-28
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The structure and conformation of Lys63-linked tetraubiquitin.
J.Mol.Biol., 392, 2009
5KYE
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BU of 5kye by Molmil
Crystal structure of USP7 catalytic domain [H294E] mutant in complex with ubiquitin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Rouge, L, Ozen, A.
登録日2016-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
Structure, 26, 2018
5GOG
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BU of 5gog by Molmil
Lys29-linked di-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-27
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.977 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5JBY
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BU of 5jby by Molmil
Lys27-linked triubiquitin
分子名称: D-ubiquitin, ubiquitin
著者Pan, M, Gao, S, Zheng, Y.
登録日2016-04-14
公開日2016-07-20
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (1.987 Å)
主引用文献Structure of Lys27-linked triubiquitin
To Be Published
2G45
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BU of 2g45 by Molmil
Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin
分子名称: CHLORIDE ION, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 5, ...
著者Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D.
登録日2006-02-21
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin.
Cell(Cambridge,Mass.), 124, 2006
2GBK
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BU of 2gbk by Molmil
Crystal Structure of the 9-10 MoaD Insertion Mutant of Ubiquitin
分子名称: Ubiquitin
著者Ferraro, D.M, Ferraro, D.J, Ramaswamy, S, Robertson, A.D.
登録日2006-03-10
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structures of Ubiquitin Insertion Mutants Support Site-specific Reflex Response to Insertions Hypothesis.
J.Mol.Biol., 359, 2006
4WLR
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BU of 4wlr by Molmil
Crystal Structure of mUCH37-hRPN13 CTD-hUb complex
分子名称: Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5
著者Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G.
登録日2014-10-07
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase.
Mol.Cell, 57, 2015
5V1Z
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BU of 5v1z by Molmil
Crystal structure of the RPN13 PRU-RPN2 (932-953)-ubiquitin complex
分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P.
登録日2017-03-02
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.
J. Biol. Chem., 292, 2017
7RMA
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BU of 7rma by Molmil
Structure of the fourth UIM (Ubiquitin Interacting Motif) of ANKRD13D in complex with a high affinity UbV (Ubiquitin Variant)
分子名称: Ankyrin repeat domain-containing protein 13D, SODIUM ION, SULFATE ION, ...
著者Singer, A.U, Manczyk, N, Veggiani, G, Sicheri, F, Sidhu, S.S.
登録日2021-07-27
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs.
Acs Chem.Biol., 17, 2022
1S1Q
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BU of 1s1q by Molmil
TSG101(UEV) domain in complex with Ubiquitin
分子名称: ACETIC ACID, COPPER (II) ION, SULFATE ION, ...
著者Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P.
登録日2004-01-07
公開日2004-05-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ubiquitin recognition by the human TSG101 protein
Mol.Cell, 13, 2004
5LRW
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BU of 5lrw by Molmil
Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin
分子名称: GLYCEROL, OTU domain-containing protein 7B, Polyubiquitin-B
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
2GBR
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BU of 2gbr by Molmil
Crystal Structure of the 35-36 MoaD Insertion Mutant of Ubiquitin
分子名称: CADMIUM ION, Ubiquitin
著者Ferraro, D.M, Ferraro, D.J, Ramaswamy, S, Robertson, A.D.
登録日2006-03-10
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Ubiquitin Insertion Mutants Support Site-specific Reflex Response to Insertions Hypothesis.
J.Mol.Biol., 359, 2006
5JG6
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BU of 5jg6 by Molmil
APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C
分子名称: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION
著者Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A.
登録日2016-04-19
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0013 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5YDR
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BU of 5ydr by Molmil
Structure of DNMT1 RFTS domain in complex with ubiquitin
分子名称: DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ...
著者Qian, C.
登録日2017-09-14
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.
Nucleic Acids Res., 46, 2018
6K9P
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BU of 6k9p by Molmil
Structure of Deubiquitinase
分子名称: Ubiquitin, Ubiquitin thioesterase
著者Lu, L.N, Liu, L, Wang, F.
登録日2019-06-17
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
7OJE
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BU of 7oje by Molmil
Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ...
著者Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U.
登録日2021-05-14
公開日2022-02-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.
Nat Commun, 13, 2022
7AI1
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BU of 7ai1 by Molmil
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
6JB7
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BU of 6jb7 by Molmil
Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H.
登録日2019-01-25
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution
To Be Published
5DFL
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BU of 5dfl by Molmil
Crystal structure of Ube2K~Ubiquitin conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Middleton, A.J, Day, C.L.
登録日2015-08-27
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K.
Sci Rep, 5, 2015
6QML
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BU of 6qml by Molmil
UCHL3 in complex with synthetic, K27-linked diubiquitin
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
著者Murachelli, A.G, Sixma, T.K.
登録日2019-02-07
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap.
Cell Chem Biol, 28, 2021
5JBV
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BU of 5jbv by Molmil
Lys27-linked triubiquitin
分子名称: D-ubiquitin, NITRATE ION, Ubiquitin
著者Pan, M, Gao, S, Zheng, Y.
登録日2016-04-13
公開日2016-05-18
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Structure of Lys27-linked triubiquitin
To Be Published
8DMS
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BU of 8dms by Molmil
Crystal structure of Legionella pneumophila macrodomain MavL in complex with ubiquitin vinyl methyl ester soaked with ADP-ribose
分子名称: CITRATE ANION, METHYL 4-AMINOBUTANOATE, MavL, ...
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-07-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of Legionella pneumophila macrodomain MavL in complex with ubiquitin vinyl methyl ester soaked with ADP-ribose
To Be Published
5MNJ
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BU of 5mnj by Molmil
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
分子名称: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ...
著者Klejnot, M, Huang, D.T.
登録日2016-12-13
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nat. Struct. Mol. Biol., 24, 2017

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