8SE9
| Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex (Form 2) | Descriptor: | ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... | Authors: | Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. | Deposit date: | 2023-04-08 | Release date: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer. Nat Commun, 14, 2023
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8RM5
| Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'SS oligo, NHP2-like protein 1, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2024-01-05 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8S8G
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2.1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8RW1
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-02-02 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8E
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-3.1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8J
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF5) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8D
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8H
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-2.2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8I
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-eIF1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8S8F
| Structure of a yeast 48S-AUC preinitiation complex in closed conformation (model py48S-AUC-3.2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein L41-A, 40S ribosomal protein S12, ... | Authors: | Villamayor-Belinchon, L, Sharma, P, Llacer, J.L, Hussain, T. | Deposit date: | 2024-03-06 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structural basis of AUC codon discrimination during translation initiation in yeast. Nucleic Acids Res., 2024
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8SVF
| BAP1/ASXL1 bound to the H2AK119Ub Nucleosome | Descriptor: | DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ... | Authors: | Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J. | Deposit date: | 2023-05-16 | Release date: | 2023-08-30 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1. Sci Adv, 9, 2023
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8RXH
| CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN | Descriptor: | (2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid, 40S ribosomal protein S12, 40S ribosomal protein S14, ... | Authors: | Rajan, K.S, Yonath, A. | Deposit date: | 2024-02-07 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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8RXX
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8SCB
| Terminating ribosome with SRI-41315 | Descriptor: | (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... | Authors: | Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. | Deposit date: | 2023-04-05 | Release date: | 2023-12-27 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. Nat.Chem.Biol., 20, 2024
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8T4S
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8SV8
| Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex from a composite map | Descriptor: | ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... | Authors: | Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. | Deposit date: | 2023-05-15 | Release date: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer. Nat Commun, 14, 2023
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8QZS
| Cryo-EM structure of the cross-exon B-like complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-29 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QXD
| Cryo-EM structure of the cross-exon pre-B complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-24 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QP8
| Cryo-EM Structure of Pre-B Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-09-30 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R0A
| Cryo-EM structure of the cross-exon pre-B+5'ss complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-31 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QPE
| Cryo-EM Structure of Pre-B-like Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-01 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R0B
| Cryo-EM structure of the cross-exon pre-B+ATP complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-31 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QPA
| Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-01 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QPB
| Cryo-EM Structure of Pre-B+ATP Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-10-01 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QP9
| Cryo-EM Structure of Pre-B+AMPPNP Complex (core part) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ... | Authors: | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | Deposit date: | 2023-09-30 | Release date: | 2024-05-22 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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