8QP8

Cryo-EM Structure of Pre-B Complex (core part)

Summary for 8QP8

• Entry DOI: 10.2210/pdb8qp8/pdb
• EMDB information: 18544
• Descriptor: Splicing factor 3A subunit 1, RNA-binding protein 42, Pre-mRNA-processing factor 6, ... (16 entities in total)
• Functional Keywords: spliceosome, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 15
• Total formula weight: 1168892.19

Authors

Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-09-30, release date: 2024-05-22, Last modification date: 2024-06-05)

• Primary citation: Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Structural insights into the cross-exon to cross-intron spliceosome switch.; Nature, 2024; PubMed: 38778104; DOI: 10.1038/s41586-024-07458-1

Experimental method

ELECTRON MICROSCOPY (3.5 Å)