8QP9
Cryo-EM Structure of Pre-B+AMPPNP Complex (core part)
Summary for 8QP9
Entry DOI | 10.2210/pdb8qp9/pdb |
EMDB information | 18545 |
Descriptor | Splicing factor 3A subunit 1, U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, Probable ATP-dependent RNA helicase DDX23, ... (17 entities in total) |
Functional Keywords | spliceosome, splicing |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 16 |
Total formula weight | 1413715.61 |
Authors | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-09-30, release date: 2024-05-22, Last modification date: 2024-06-05) |
Primary citation | Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R. Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024 Cited by PubMed: 38778104DOI: 10.1038/s41586-024-07458-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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