PDB: 1848 resultsInfo pagesStatus searchChemie searchBIRD

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5H64	Cryo-EM structure of mTORC1 Descriptor: Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 Authors: Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. Deposit date: 2016-11-10 Release date: 2017-01-25 Last modified: 2019-11-06 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1 Protein Cell, 7, 2016
6FTG	Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal membranes Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Pfeffer, S, Foerster, F. Deposit date: 2018-02-22 Release date: 2018-03-21 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (9.1 Å) Cite: Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
7QZJ	1.55 A X-ray crystallographic structure of SapH from Streptomyces sp. (HPH0547) involved in Pseudouridimycin biosynthesis Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, GLYCEROL, ... Authors: Schnell, R, Schneider, G. Deposit date: 2022-01-31 Release date: 2023-02-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway. Acs Chem.Biol., 18, 2023
6BCX	mTORC1 structure refined to 3.0 angstroms Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, ... Authors: Pavletich, N.P, Yang, H. Deposit date: 2017-10-20 Release date: 2017-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
6BCU	Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ... Authors: Pavletich, N.P, Yang, H. Deposit date: 2017-10-20 Release date: 2017-12-20 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
6TCA	Phosphorylated p38 and MAPKAPK2 complex with inhibitor Descriptor: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide Authors: Sok, P, Remenyi, A. Deposit date: 2019-11-05 Release date: 2020-07-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.7 Å) Cite: MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases. Structure, 28, 2020
5ZCS	4.9 Angstrom Cryo-EM structure of human mTOR complex 2 Descriptor: Rapamycin-insensitive companion of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, ... Authors: Chen, X, Liu, M, Tian, Y, Wang, H, Wang, J, Xu, Y. Deposit date: 2018-02-20 Release date: 2018-03-21 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Cryo-EM structure of human mTOR complex 2. Cell Res., 28, 2018
8OO6	Pol I bound to extended and displaced DNA section - closed conformation Descriptor: DNA polymerase I, Displaced primer, Extending Primer, ... Authors: Botto, M, Borsellini, A, Lamers, M.H. Deposit date: 2023-04-04 Release date: 2023-08-09 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: A four-point molecular handover during Okazaki maturation. Nat.Struct.Mol.Biol., 30, 2023
8OOY	Pol I bound to extended and displaced DNA section - open conformation Descriptor: DNA polymerase I, Displacing Primer, Extending Primer, ... Authors: Botto, M, Borsellini, A, Lamers, M.H. Deposit date: 2023-04-06 Release date: 2023-08-09 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (4 Å) Cite: A four-point molecular handover during Okazaki maturation. Nat.Struct.Mol.Biol., 30, 2023
6Z2J	The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex Descriptor: Deoxynucleotidyltransferase terminal-interacting protein 1, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ... Authors: Fairall, L, Saleh, A, Ragan, T.J, Millard, C.J, Savva, C.G, Schwabe, J.W.R. Deposit date: 2020-05-16 Release date: 2020-07-08 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4 Å) Cite: The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure. Nat Commun, 11, 2020
7R5K	Human nuclear pore complex (constricted) Descriptor: Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... Authors: Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. Deposit date: 2022-02-10 Release date: 2022-06-22 Last modified: 2022-06-29 Method: ELECTRON MICROSCOPY (12 Å) Cite: AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science, 376, 2022
7R5J	Human nuclear pore complex (dilated) Descriptor: Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... Authors: Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. Deposit date: 2022-02-10 Release date: 2022-09-21 Last modified: 2022-12-21 Method: ELECTRON MICROSCOPY (50 Å) Cite: AI-based structure prediction empowers integrative structural analysis of human nuclear pores Science, 376, 2022
7K1J	CryoEM structure of inactivated-form DNA-PK (Complex III) Descriptor: DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... Authors: Chen, X, Gellert, M, Yang, W. Deposit date: 2020-09-07 Release date: 2021-01-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
7WU7	Prefoldin-tubulin-TRiC complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... Authors: Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. Deposit date: 2022-02-07 Release date: 2022-12-21 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (3.85 Å) Cite: Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
4GUA	Alphavirus P23pro-zbd Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Non-structural polyprotein, SULFATE ION, ... Authors: Shin, G, Yost, S, Miller, M, Marcotrigiano, J. Deposit date: 2012-08-29 Release date: 2012-10-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.854 Å) Cite: Structural and functional insights into alphavirus polyprotein processing and pathogenesis. Proc.Natl.Acad.Sci.USA, 109, 2012
7P27	NMR solution structure of Chikungunya virus macro domain Descriptor: Polyprotein P1234 Authors: Lykouras, M.V, Tsika, A.C, Papageorgiou, N, Canard, B, Coutard, B, Bentrop, D, Spyroulias, G.A. Deposit date: 2021-07-04 Release date: 2022-07-13 Last modified: 2024-06-19 Method: SOLUTION NMR Cite: Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity. J.Mol.Biol., 434, 2022
7PLO	H. sapiens replisome-CUL2/LRR1 complex Descriptor: Cell division control protein 45 homolog, Claspin, Cullin-2, ... Authors: Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M. Deposit date: 2021-09-01 Release date: 2021-11-10 Last modified: 2023-10-18 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
1RM1	Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex Descriptor: 5'-D(*AP*TP*CP*GP*AP*TP*CP*GP*AP*TP*AP*TP*AP*AP*AP*AP*CP*G)-3', 5'-D(P*CP*GP*TP*TP*TP*TP*AP*TP*AP*TP*CP*GP*AP*TP*CP*GP*AP*T)-3', TATA-box binding protein, ... Authors: Jin, X, Gewirth, D.T, Geiger, J.H. Deposit date: 2003-11-26 Release date: 2005-07-26 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: High Resolution Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex TO BE PUBLISHED
6MW6	Antimicrobial lasso peptide citrocin Descriptor: Citrocin Authors: Link, A.J, Cheung-Lee, W.L. Deposit date: 2018-10-29 Release date: 2019-03-13 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Discovery and structure of the antimicrobial lasso peptide citrocin. J.Biol.Chem., 294, 2019
8V6V	Cryo-EM structure of doubly-bound SNF2h-nucleosome complex Descriptor: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ... Authors: Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y. Deposit date: 2023-12-03 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nat Commun, 15, 2024
8V4Y	Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 1) Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Histone H2A type 1, ... Authors: Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y. Deposit date: 2023-11-29 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nat Commun, 15, 2024
8V7L	Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ... Authors: Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y. Deposit date: 2023-12-04 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nat Commun, 15, 2024
7LUV	Cryo-EM structure of the yeast THO-Sub2 complex Descriptor: ATP-dependent RNA helicase SUB2, THO complex subunit 2, THO complex subunit HPR1, ... Authors: Xie, Y, Ren, Y. Deposit date: 2021-02-23 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2. Elife, 10, 2021
8FVI	Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 Descriptor: Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ... Authors: Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. Deposit date: 2023-01-19 Release date: 2023-09-06 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H. Nat Commun, 14, 2023
6EZE	The open conformation of E.coli Elongation Factor Tu in complex with GDPNP. Descriptor: DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ... Authors: Johansen, J.S, Blaise, M, Thirup, S.S. Deposit date: 2017-11-15 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.47 Å) Cite: E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form. Nucleic Acids Res., 46, 2018

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