7P27
NMR solution structure of Chikungunya virus macro domain
Summary for 7P27
| Entry DOI | 10.2210/pdb7p27/pdb |
| NMR Information | BMRB: 27158 |
| Descriptor | Polyprotein P1234 (1 entity in total) |
| Functional Keywords | chikv, macro domain, viral replication, adp-ribose, viral protein |
| Biological source | Chikungunya virus (strain S27-African prototype) (CHIKV) |
| Total number of polymer chains | 1 |
| Total formula weight | 18635.12 |
| Authors | Lykouras, M.V.,Tsika, A.C.,Papageorgiou, N.,Canard, B.,Coutard, B.,Bentrop, D.,Spyroulias, G.A. (deposition date: 2021-07-04, release date: 2022-07-13, Last modification date: 2024-06-19) |
| Primary citation | Tsika, A.C.,Gallo, A.,Fourkiotis, N.K.,Argyriou, A.I.,Sreeramulu, S.,Lohr, F.,Rogov, V.V.,Richter, C.,Linhard, V.,Gande, S.L.,Altincekic, N.,Krishnathas, R.,Elamri, I.,Schwalbe, H.,Wollenhaupt, J.,Weiss, M.S.,Spyroulias, G.A. Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity. J.Mol.Biol., 434:167720-167720, 2022 Cited by PubMed: 35839840DOI: 10.1016/j.jmb.2022.167720 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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