7PLO

H. sapiens replisome-CUL2/LRR1 complex

This is a non-PDB format compatible entry.

Summary for 7PLO

• Entry DOI: 10.2210/pdb7plo/pdb
• EMDB information: 13490 13491 13492 13494
• Descriptor: DNA replication licensing factor MCM2, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... (28 entities in total)
• Functional Keywords: genome stability, dna replication, ubiquitination, termination, replisome, cryo-em, cmg, cul2lrr1, replication, dna, polymerase, helicase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 26
• Total formula weight: 1964966.14

Authors

Jones, M.J.,Yeeles, J.T.P.,Deegan, T.D.,Jenkyn-Bedford, M. (deposition date: 2021-09-01, release date: 2021-11-10, Last modification date: 2023-10-18)

• Primary citation: Jenkyn-Bedford, M.,Jones, M.L.,Baris, Y.,Labib, K.P.M.,Cannone, G.,Yeeles, J.T.P.,Deegan, T.D.; A conserved mechanism for regulating replisome disassembly in eukaryotes.; Nature, 600:743-747, 2021; PubMed: 34700328; DOI: 10.1038/s41586-021-04145-3

Experimental method

ELECTRON MICROSCOPY (2.8 Å)