8FVI

Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5

Summary for 8FVI

• Entry DOI: 10.2210/pdb8fvi/pdb
• EMDB information: 29488 29489 29490
• Descriptor: Core-binding factor subunit beta, Virion infectivity factor, DNA dC->dU-editing enzyme APOBEC-3H, ... (10 entities in total)
• Functional Keywords: virus-host protein complex, antiviral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 126941.56

Authors

Ito, F.,Alvarez-Cabrera, A.L.,Zhou, Z.H.,Chen, X.S. (deposition date: 2023-01-19, release date: 2023-09-06)

• Primary citation: Ito, F.,Alvarez-Cabrera, A.L.,Kim, K.,Zhou, Z.H.,Chen, X.S.; Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H; Nat Commun, 14:5241-, 2023; DOI: 10.1038/s41467-023-40955-x

Experimental method

ELECTRON MICROSCOPY (3.24 Å)