6Z2J
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Summary for 6Z2J
Entry DOI | 10.2210/pdb6z2j/pdb |
EMDB information | 11041 |
Descriptor | Histone deacetylase 1, Deoxynucleotidyltransferase terminal-interacting protein 1, Mitotic deacetylase-associated SANT domain protein, ... (6 entities in total) |
Functional Keywords | hdac1 mideas elmsan1 dnttip1 tdif1 histone deacetylase midac, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 180317.22 |
Authors | Fairall, L.,Saleh, A.,Ragan, T.J.,Millard, C.J.,Savva, C.G.,Schwabe, J.W.R. (deposition date: 2020-05-16, release date: 2020-07-08, Last modification date: 2024-05-22) |
Primary citation | Turnbull, R.E.,Fairall, L.,Saleh, A.,Kelsall, E.,Morris, K.L.,Ragan, T.J.,Savva, C.G.,Chandru, A.,Millard, C.J.,Makarova, O.V.,Smith, C.J.,Roseman, A.M.,Fry, A.M.,Cowley, S.M.,Schwabe, J.W.R. The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure. Nat Commun, 11:3252-3252, 2020 Cited by PubMed: 32591534DOI: 10.1038/s41467-020-17078-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)