6Z2J
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, E) | Histone deacetylase 1 | polymer | 482 | 55178.9 | 2 | UniProt (Q13547) Pfam (PF00850) | Homo sapiens (Human) | HD1 |
| 2 | C, D (A, B) | Deoxynucleotidyltransferase terminal-interacting protein 1 | polymer | 130 | 14381.3 | 2 | UniProt (Q9H147) Pfam (PF18192) | Homo sapiens (Human) | Terminal deoxynucleotidyltransferase-interacting factor 1,TdT-interacting factor 1 |
| 3 | E, F (F, D) | Mitotic deacetylase-associated SANT domain protein | polymer | 173 | 19794.8 | 2 | UniProt (Q6PJG2) Pfam (PF01448) | Homo sapiens (Human) | ELM2 and SANT domain-containing protein 1 |
| 4 | G, K (C, E) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) | |||
| 5 | H, L (C, E) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | I, J, M, N (C, E) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) |
Sequence modifications
F, D: 717 - 887 (UniProt: Q6PJG2)
| PDB | External Database | Details |
|---|---|---|
| Gly 715 | - | expression tag |
| Ala 716 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 178709.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1607.3 | |
| All* | Total formula weight | 180317.2 |
