7QZJ

1.55 A X-ray crystallographic structure of SapH from Streptomyces sp. (HPH0547) involved in Pseudouridimycin biosynthesis

Summary for 7QZJ

• Entry DOI: 10.2210/pdb7qzj/pdb
• Descriptor: Aspartate aminotransferase family protein, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: pseudouridimycin, streptomyces, antibiotics, pyridoxal phosphate, secondary metabolism, biosynthetic protein
• Biological source: Streptomyces sp. HPH0547
• Total number of polymer chains: 2
• Total formula weight: 96256.18

Authors

Schnell, R.,Schneider, G. (deposition date: 2022-01-31, release date: 2023-02-15, Last modification date: 2024-02-07)

• Primary citation: Artukka, E.,Schnell, R.,Palmu, K.,Rosenqvist, P.,Szodorai, E.,Niemi, J.,Virta, P.,Schneider, G.,Metsa-Ketela, M.; Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway.; Acs Chem.Biol., 18:794-802, 2023; PubMed: 37005433; DOI: 10.1021/acschembio.2c00826

Experimental method

X-RAY DIFFRACTION (1.55 Å)