3VE6
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2QNA
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![BU of 2qna by Molmil](/molmil-images/mine/2qna) | Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65) | Descriptor: | Importin subunit beta-1, SULFATE ION, Snurportin-1 | Authors: | Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R. | Deposit date: | 2007-07-18 | Release date: | 2008-04-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374, 2007
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7LF4
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7DVQ
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![BU of 7dvq by Molmil](/molmil-images/mine/7dvq) | Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | Authors: | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | Deposit date: | 2021-01-14 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure of the activated human minor spliceosome. Science, 371, 2021
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1M5N
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![BU of 1m5n by Molmil](/molmil-images/mine/1m5n) | Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP | Descriptor: | Importin beta-1 subunit, Parathyroid hormone-related protein | Authors: | Cingolani, G, Bednenko, J, Gillespie, M.T, Gerace, L. | Deposit date: | 2002-07-09 | Release date: | 2003-01-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular basis for the recognition
of a nonclassical nuclear localization
signal by importin beta Mol.Cell, 10, 2002
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3T7U
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![BU of 3t7u by Molmil](/molmil-images/mine/3t7u) | A NeW Crystal structure of APC-ARM | Descriptor: | Adenomatous polyposis coli protein, PHOSPHATE ION | Authors: | Zhang, Z, Wu, G. | Deposit date: | 2011-07-31 | Release date: | 2011-12-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the armadillo repeat domain of adenomatous polyposis coli which reveals its inherent flexibility Biochem.Biophys.Res.Commun., 412, 2011
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4TNM
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2BCT
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1EJY
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6KBM
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![BU of 6kbm by Molmil](/molmil-images/mine/6kbm) | Crystal structure of Vac8 bound to Atg13 | Descriptor: | Autophagy-related protein 13, Vacuolar protein 8 | Authors: | Park, J, Lee, C. | Deposit date: | 2019-06-25 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.902 Å) | Cite: | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways. Autophagy, 16, 2020
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3OUW
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![BU of 3ouw by Molmil](/molmil-images/mine/3ouw) | Structure of beta-catenin with Lef-1 | Descriptor: | Catenin beta-1, Lymphoid enhancer-binding factor 1 | Authors: | Weis, W.I, Sun, J. | Deposit date: | 2010-09-15 | Release date: | 2010-11-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Biochemical and structural characterization of beta-catenin interactions with nonphosphorylated and CK2-phosphorylated Lef-1. J.Mol.Biol., 405, 2011
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5IZ9
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![BU of 5iz9 by Molmil](/molmil-images/mine/5iz9) | Protein-protein interaction | Descriptor: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | Deposit date: | 2016-03-25 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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5XZX
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3L6Y
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![BU of 3l6y by Molmil](/molmil-images/mine/3l6y) | Crystal structure of p120 catenin in complex with E-cadherin | Descriptor: | Catenin delta-1, E-cadherin | Authors: | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | Deposit date: | 2009-12-27 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.), 141, 2010
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8FZM
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![BU of 8fzm by Molmil](/molmil-images/mine/8fzm) | |
1I7X
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![BU of 1i7x by Molmil](/molmil-images/mine/1i7x) | BETA-CATENIN/E-CADHERIN COMPLEX | Descriptor: | BETA-CATENIN, EPITHELIAL-CADHERIN | Authors: | Huber, A.H, Weis, W.I. | Deposit date: | 2001-03-10 | Release date: | 2001-05-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Cell(Cambridge,Mass.), 105, 2001
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4HTV
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3NMZ
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![BU of 3nmz by Molmil](/molmil-images/mine/3nmz) | Crystal structure of APC complexed with Asef | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | Deposit date: | 2010-06-23 | Release date: | 2011-07-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
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4DJS
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![BU of 4djs by Molmil](/molmil-images/mine/4djs) | Structure of beta-catenin in complex with a stapled peptide inhibitor | Descriptor: | Catenin beta-1, stapled peptide RRWPQ(MK8)ILD(MK8)HVRRVWR | Authors: | Bowman, B.R, Grossmann, T.N, Yeh, J.T.-H, Verdine, G.L. | Deposit date: | 2012-02-02 | Release date: | 2012-10-17 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (3.029 Å) | Cite: | Inhibition of oncogenic Wnt signaling through direct targeting of beta-catenin. Proc.Natl.Acad.Sci.USA, 109, 2012
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5IZ8
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![BU of 5iz8 by Molmil](/molmil-images/mine/5iz8) | Protein-protein interaction | Descriptor: | ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein, TRIETHYLENE GLYCOL | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | Deposit date: | 2016-03-25 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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1JPP
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3LWW
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![BU of 3lww by Molmil](/molmil-images/mine/3lww) | |
4U2X
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![BU of 4u2x by Molmil](/molmil-images/mine/4u2x) | Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus | Descriptor: | CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 | Authors: | Xu, W, Leung, D, Borek, D, Amarasinghe, G. | Deposit date: | 2014-07-18 | Release date: | 2014-08-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.153 Å) | Cite: | Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
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6KBN
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![BU of 6kbn by Molmil](/molmil-images/mine/6kbn) | Crystal structure of Vac8 (del 19-33) bound to Atg13 | Descriptor: | Autophagy-related protein 13, Vacuolar protein 8 | Authors: | Park, J, Lee, C. | Deposit date: | 2019-06-25 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways. Autophagy, 16, 2020
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7N8J
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![BU of 7n8j by Molmil](/molmil-images/mine/7n8j) | |