7LF4
Structure of importin a3 bound to the p50- and p65-NLSs
Summary for 7LF4
Entry DOI | 10.2210/pdb7lf4/pdb |
Descriptor | Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65 (3 entities in total) |
Functional Keywords | nuclear import, importin alpha 3, nls, nf-kb, p50, p65, protein transport |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 125243.82 |
Authors | Florio, T.J.,Lokareddy, R.K.,Cingolani, G. (deposition date: 2021-01-15, release date: 2022-01-19, Last modification date: 2023-10-25) |
Primary citation | Florio, T.J.,Lokareddy, R.K.,Yeggoni, D.P.,Sankhala, R.S.,Ott, C.A.,Gillilan, R.E.,Cingolani, G. Differential recognition of canonical NF-kappa B dimers by Importin alpha 3. Nat Commun, 13:1207-1207, 2022 Cited by PubMed: 35260573DOI: 10.1038/s41467-022-28846-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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