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7LF4

Structure of importin a3 bound to the p50- and p65-NLSs

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Importin subunit alpha-3polymer52157941.42UniProt (O00629)
Pfam (PF01749)
Pfam (PF16186)
Pfam (PF00514)
Homo sapiens (Human)Importin alpha Q1,Qip1,Karyopherin subunit alpha-4
2B, E
(B, F)
Nuclear factor NF-kappa-B p105 subunitpolymer141790.12UniProt (P19838)Homo sapiensDNA-binding factor KBF1,EBP-1,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
3D, F
(D, E)
Transcription factor p65polymer222890.42UniProt (Q04206)Homo sapiensNuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight125243.8
All*Total formula weight125243.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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