7LF4

Structure of importin a3 bound to the p50- and p65-NLSs

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Importin subunit alpha-3	polymer	521	57941.4	2	UniProt (O00629) Pfam (PF01749) Pfam (PF16186) Pfam (PF00514) In PDB	Homo sapiens (Human)	Importin alpha Q1,Qip1,Karyopherin subunit alpha-4
2	B, F	Nuclear factor NF-kappa-B p105 subunit	polymer	14	1790.1	2	UniProt (P19838) In PDB	Homo sapiens	DNA-binding factor KBF1,EBP-1,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
3	D, E	Transcription factor p65	polymer	22	2890.4	2	UniProt (Q04206) In PDB	Homo sapiens	Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	125243.8
All*	Total formula weight	125243.8

*Water molecules are not included.