1JPP

The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin

Summary for 1JPP

Entry DOI	10.2210/pdb1jpp/pdb
Descriptor	BETA-CATENIN, ADENOMATOUS POLYPOSIS COLI PROTEIN, GLYCEROL, ... (4 entities in total)
Functional Keywords	disease mutation, anti-oncogene, cell adhesion
Biological source	Mus musculus (house mouse) More
Cellular location	Cytoplasm: Q02248 Cell junction, adherens junction: P25054
Total number of polymer chains	4
Total formula weight	121354.15
Authors	Spink, K.E.,Fridman, S.G.,Weis, W.I. (deposition date: 2001-08-02, release date: 2002-01-16, Last modification date: 2023-08-16)
Primary citation	Eklof Spink, K.,Fridman, S.G.,Weis, W.I. Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. EMBO J., 20:6203-6212, 2001 Cited by PubMed: 11707392 DOI: 10.1093/emboj/20.22.6203 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation