1JPP
The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007155 | biological_process | cell adhesion |
| A | 0045296 | molecular_function | cadherin binding |
| B | 0007155 | biological_process | cell adhesion |
| B | 0045296 | molecular_function | cadherin binding |
| C | 0008013 | molecular_function | beta-catenin binding |
| C | 0016055 | biological_process | Wnt signaling pathway |
| D | 0008013 | molecular_function | beta-catenin binding |
| D | 0016055 | biological_process | Wnt signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 672 |
| Chain | Residue |
| A | GLU182 |
| A | ARG185 |
| A | HIS186 |
| A | HIS224 |
| B | GLU267 |
| B | GLY268 |
| B | LYS270 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by FYN and PTK6 => ECO:0000269|PubMed:12640114 |
| Chain | Residue | Details |
| A | TYR142 | |
| B | TYR142 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | SER191 | |
| B | SER191 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by CDK5 => ECO:0000250|UniProtKB:P35222 |
| Chain | Residue | Details |
| A | SER246 | |
| B | SER246 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P35222 |
| Chain | Residue | Details |
| A | TYR331 | |
| A | TYR333 | |
| B | TYR331 | |
| B | TYR333 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by AMPK => ECO:0000269|PubMed:20361929, ECO:0007744|PubMed:17242355 |
| Chain | Residue | Details |
| A | SER552 | |
| B | SER552 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P35222 |
| Chain | Residue | Details |
| A | THR556 | |
| B | THR556 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:20705246 |
| Chain | Residue | Details |
| A | CYS619 | |
| B | CYS619 |
