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PDB: 284 results

3MHS
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BU of 3mhs by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
Authors:Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
Deposit date:2010-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
3B0A
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BU of 3b0a by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
Descriptor: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, TRIS(HYDROXYETHYL)AMINOMETHANE, ...
Authors:Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
Deposit date:2011-06-07
Release date:2011-12-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
3ZNZ
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BU of 3znz by Molmil
Crystal structure of OTULIN OTU domain (C129A) in complex with Met1- di ubiquitin
Descriptor: POLYUBIQUITIN-C, PROTEIN FAM105B, SULFATE ION
Authors:Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
Deposit date:2013-02-18
Release date:2013-06-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3H7P
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BU of 3h7p by Molmil
Crystal structure of K63-linked di-ubiquitin
Descriptor: CADMIUM ION, Ubiquitin
Authors:Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
Deposit date:2009-04-28
Release date:2009-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture.
Proteins, 77, 2009
4LDT
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BU of 4ldt by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ...
Authors:Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C.
Deposit date:2013-06-25
Release date:2013-08-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat.Struct.Mol.Biol., 20, 2013
3TMP
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BU of 3tmp by Molmil
The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde
Descriptor: OTU domain-containing protein 5, Polyubiquitin-C
Authors:Ma, X, Yin, J, Hymowitz, S, Starovasnik, M, Cochran, A.
Deposit date:2011-08-31
Release date:2012-01-11
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Phosphorylation-dependent activity of the deubiquitinase DUBA.
Nat.Struct.Mol.Biol., 19, 2012
6N6R
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BU of 6n6r by Molmil
Crystal structure of ABIN-1 UBAN in complex with two M1-linked di-ubiquitins
Descriptor: TNFAIP3-interacting protein 1, Ubiquitin
Authors:Rahighi, S, Dikic, I, Wakatsuki, S.
Deposit date:2018-11-27
Release date:2019-07-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains.
J.Mol.Biol., 431, 2019
2JF5
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BU of 2jf5 by Molmil
crystal structure of Lys63-linked di-ubiquitin
Descriptor: CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ...
Authors:Komander, D, Odenwaelder, P, Barford, D.
Deposit date:2007-01-26
Release date:2008-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains.
Embo Rep., 10, 2009
3VUW
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BU of 3vuw by Molmil
Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I
Descriptor: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ...
Authors:Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2012-07-09
Release date:2013-02-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
Embo J., 31, 2012
4MSQ
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BU of 4msq by Molmil
Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to ubiquitin
Descriptor: 1,2-ETHANEDIOL, AMSH-like protease sst2, PHOSPHATE ION, ...
Authors:Shrestha, R.K, Ronau, J.A, Das, C.
Deposit date:2013-09-18
Release date:2014-06-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
3HM3
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BU of 3hm3 by Molmil
The Structure and conformation of Lys-63 linked tetra-ubiquitin
Descriptor: Ubiquitin, ZINC ION
Authors:Datta, A.B, Hura, G.L, Wolberger, C.
Deposit date:2009-05-28
Release date:2009-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The structure and conformation of Lys63-linked tetraubiquitin.
J.Mol.Biol., 392, 2009
6ULH
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BU of 6ulh by Molmil
Structure of MavC in complex with its substrate in R3 spacegroup
Descriptor: LPG2147 (MavC), Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Iyer, S, Puvar, K, Das, C.
Deposit date:2019-10-08
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
3VUY
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BU of 3vuy by Molmil
Crystal structure of A20 ZF7 in complex with linear tetraubiquitin
Descriptor: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ...
Authors:Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2012-07-09
Release date:2013-02-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.981 Å)
Cite:Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
Embo J., 31, 2012
2G45
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BU of 2g45 by Molmil
Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin
Descriptor: CHLORIDE ION, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 5, ...
Authors:Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D.
Deposit date:2006-02-21
Release date:2006-04-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin.
Cell(Cambridge,Mass.), 124, 2006
2GBK
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BU of 2gbk by Molmil
Crystal Structure of the 9-10 MoaD Insertion Mutant of Ubiquitin
Descriptor: Ubiquitin
Authors:Ferraro, D.M, Ferraro, D.J, Ramaswamy, S, Robertson, A.D.
Deposit date:2006-03-10
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structures of Ubiquitin Insertion Mutants Support Site-specific Reflex Response to Insertions Hypothesis.
J.Mol.Biol., 359, 2006
4IG7
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BU of 4ig7 by Molmil
Crystal structure of Trichinella spiralis UCH37 bound to Ubiquitin vinyl methyl ester
Descriptor: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin C-terminal hydrolase 37
Authors:Das, C, Kim, M.I, Morrow, M.E.
Deposit date:2012-12-16
Release date:2013-05-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.996 Å)
Cite:Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C‑Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.
Biochemistry, 52, 2013
8T48
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BU of 8t48 by Molmil
The N4BP1 CUE-like domain in complex with linear di-Ubiquitin
Descriptor: Di-Ubiquitin, GLYCEROL, LITHIUM ION, ...
Authors:Schubert, A.F, Harris, S.F.
Deposit date:2023-06-08
Release date:2024-03-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:N4BP1 coordinates ubiquitin-dependent crosstalk within the I kappa B kinase family to limit Toll-like receptor signaling and inflammation.
Immunity, 57, 2024
1S1Q
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BU of 1s1q by Molmil
TSG101(UEV) domain in complex with Ubiquitin
Descriptor: ACETIC ACID, COPPER (II) ION, SULFATE ION, ...
Authors:Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P.
Deposit date:2004-01-07
Release date:2004-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ubiquitin recognition by the human TSG101 protein
Mol.Cell, 13, 2004
2GBR
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BU of 2gbr by Molmil
Crystal Structure of the 35-36 MoaD Insertion Mutant of Ubiquitin
Descriptor: CADMIUM ION, Ubiquitin
Authors:Ferraro, D.M, Ferraro, D.J, Ramaswamy, S, Robertson, A.D.
Deposit date:2006-03-10
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Ubiquitin Insertion Mutants Support Site-specific Reflex Response to Insertions Hypothesis.
J.Mol.Biol., 359, 2006
4V3K
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BU of 4v3k by Molmil
RNF38-UbcH5B-UB complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF38, ...
Authors:Buetow, L, Gabrielsen, M, Anthony, N.G, Dou, H, Patel, A, Aitkenhead, H, Sibbet, G.J, Smith, B.O, Huang, D.T.
Deposit date:2014-10-20
Release date:2015-04-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin.
Mol.Cell, 58, 2015
4FJV
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BU of 4fjv by Molmil
Crystal Structure of Human Otubain2 and Ubiquitin Complex
Descriptor: ETHANAMINE, GLYCEROL, Polyubiquitin-C, ...
Authors:Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M.
Deposit date:2012-06-12
Release date:2013-06-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.
Plos One, 10, 2015
7MIC
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BU of 7mic by Molmil
Maize rayado fino virus protease in complex with Ubiquitin
Descriptor: 3-AMINOPROPANE, GLYCEROL, RNA replication protein, ...
Authors:Patel, A, Mark, B.L.
Deposit date:2021-04-16
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase.
J.Biol.Chem., 297, 2021
6P5B
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BU of 6p5b by Molmil
Crystal Structure of MavC in Complex with Ub-UbE2N
Descriptor: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
Authors:Puvar, K, Iyer, S, Negron Teron, K.I, Das, C.
Deposit date:2019-05-30
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6W9S
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BU of 6w9s by Molmil
Crystal structure of an OTU deubiquitinase from Escherichia albertii bound to ubiquitin
Descriptor: FORMIC ACID, OTU domain-containing protein EschOTU, Ubiquitin
Authors:Schubert, A.F, Pruneda, J.N, Komander, D.
Deposit date:2020-03-23
Release date:2020-07-01
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
8FTQ
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BU of 8ftq by Molmil
Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44
Descriptor: N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
Authors:Walters, K.J, Lu, X, Chandravanshi, M.
Deposit date:2023-01-13
Release date:2024-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins.
Nat Commun, 15, 2024

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