Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1273 件

7D77
DownloadVisualize
BU of 7d77 by Molmil
Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Adhesion G protein-coupled receptor G3; GPR97, CHOLESTEROL, ...
著者Ping, Y, Mao, C, Xiao, P, Zhao, R, Jiang, Y, Yang, Z, An, W, Shen, D, Yang, F, Zhang, H, Qu, C, Shen, Q, Tian, C, Li, Z, Li, S, Wang, G, Tao, X, Wen, X, Zhong, Y, Yang, J, Yi, F, Yu, X, Xu, E, Zhang, Y, Sun, J.
登録日2020-10-03
公開日2021-02-03
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.
Nature, 589, 2021
7D76
DownloadVisualize
BU of 7d76 by Molmil
Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex
分子名称: (8~{S},9~{R},10~{S},11~{S},13~{S},14~{S},16~{S},17~{R})-9-chloranyl-10,13,16-trimethyl-11,17-bis(oxidanyl)-17-(2-oxidanylethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, Adhesion G protein-coupled receptor G3; GPR97, CHOLESTEROL, ...
著者Ping, Y, Mao, C, Xiao, P, Zhao, R, Jiang, Y, Yang, Z, An, W, Shen, D, Yang, F, Zhang, H, Qu, C, Shen, Q, Tian, C, Li, Z, Li, S, Wang, G, Tao, X, Wen, X, Zhong, Y, Yang, J, Yi, F, Yu, X, Xu, E, Zhang, Y, Sun, J.
登録日2020-10-03
公開日2021-02-03
最終更新日2021-02-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.
Nature, 589, 2021
4EHQ
DownloadVisualize
BU of 4ehq by Molmil
Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode
分子名称: CALCIUM ION, Calcium release-activated calcium channel protein 1, Calmodulin, ...
著者Liu, Y, Zheng, X, Mueller, G.A, Sobhany, M, DeRose, E.F, Zhang, Y, London, R.E, Birnbaumer, L.
登録日2012-04-03
公開日2012-11-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9005 Å)
主引用文献Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.
J.Biol.Chem., 287, 2012
3EPO
DownloadVisualize
BU of 3epo by Molmil
Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P
分子名称: (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE, Thiamine biosynthesis protein thiC
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
6V4X
DownloadVisualize
BU of 6v4x by Molmil
Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution
分子名称: Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ...
著者Sun, Y, Zhang, Y, Walz, T, Tong, L.
登録日2019-12-02
公開日2020-02-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of an active human histone pre-mRNA 3'-end processing machinery.
Science, 367, 2020
6VX7
DownloadVisualize
BU of 6vx7 by Molmil
bestrophin-2 Ca2+-bound state (5 mM Ca2+)
分子名称: Bestrophin, CALCIUM ION, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.36 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
8K14
DownloadVisualize
BU of 8k14 by Molmil
X-ray crystal structure of 18a in BRD4(1)
分子名称: 4-[8-methoxy-2-methyl-1-(1-phenylethyl)imidazo[4,5-c]quinolin-7-yl]-3,5-dimethyl-1,2-oxazole, Bromodomain-containing protein 4
著者Xu, H, Shen, H, Zhang, Y, Xu, Y, Li, R.
登録日2023-07-10
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation.
Eur.J.Med.Chem., 263, 2024
6WEK
DownloadVisualize
BU of 6wek by Molmil
Structure of cGMP-bound WT TAX-4 reconstituted in lipid nanodiscs
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ...
著者Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
登録日2020-04-02
公開日2020-06-03
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
6WEL
DownloadVisualize
BU of 6wel by Molmil
Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
著者Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
登録日2020-04-02
公開日2020-06-03
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
8HDZ
DownloadVisualize
BU of 8hdz by Molmil
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form
分子名称: A22 DNA replication processivity factor, E4 uracil-DNA glycosylase, F8 DNA polymerase
著者Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C.
登録日2022-11-07
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.
Cell Res., 33, 2023
6VX8
DownloadVisualize
BU of 6vx8 by Molmil
bestrophin-2 Ca2+- unbound state 2 (EGTA only)
分子名称: Bestrophin, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
6VX9
DownloadVisualize
BU of 6vx9 by Molmil
bestrophin-2 Ca2+- unbound state 1 (EGTA only)
分子名称: Bestrophin, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.17 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
8J6R
DownloadVisualize
BU of 8j6r by Molmil
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
分子名称: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
登録日2023-04-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8J6Q
DownloadVisualize
BU of 8j6q by Molmil
Cryo-EM structure of the 3-HB and compound 9n-bound human HCAR2-Gi1 complex
分子名称: (3R)-3-hydroxybutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, ...
著者Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
登録日2023-04-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
8J6P
DownloadVisualize
BU of 8j6p by Molmil
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, ...
著者Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y.
登録日2023-04-26
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Nat Commun, 14, 2023
6WF4
DownloadVisualize
BU of 6wf4 by Molmil
Crystal Structure of TerC Co-crystallized with Polyporic Acid
分子名称: (2~5~S)-2~3~,2~5~,2~6~-trihydroxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~(2~5~H)-one, ISOPROPYL ALCOHOL, Terfestatin Biosyntheis Enzyme C
著者Clinger, J.A, Miller, M.D, Hall, R.E, Zhang, Y, Elshahawi, S.I, Thorson, J.S, Van Lanen, S.G, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2020-04-03
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and functional characterization of two cooperative enzymes responsible for the stability of p-terphenyls.
To be published
3EPM
DownloadVisualize
BU of 3epm by Molmil
Crystal structure of Caulobacter crescentus ThiC
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SULFATE ION, Thiamine biosynthesis protein thiC, ...
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
3EPN
DownloadVisualize
BU of 3epn by Molmil
Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide
分子名称: 1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole, Thiamine biosynthesis protein thiC
著者Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E.
登録日2008-09-29
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily
Nat.Chem.Biol., 4, 2008
6O6L
DownloadVisualize
BU of 6o6l by Molmil
The Structure of EgtB(Cabther) in complex with Hercynine
分子名称: EgtB (Cabther), FE (III) ION, N,N,N-trimethyl-histidine
著者Irani, S, Zhang, Y.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity.
Acs Catalysis, 9, 2019
6VX6
DownloadVisualize
BU of 6vx6 by Molmil
bestrophin-2 Ca2+-bound state (250 nM Ca2+)
分子名称: Bestrophin, CALCIUM ION, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
6VX5
DownloadVisualize
BU of 6vx5 by Molmil
bestrophin-2 Ca2+- unbound state (250 nM Ca2+)
分子名称: Bestrophin, CHLORIDE ION
著者Owji, A.P, Zhao, Q, Ji, C, Kittredge, A, Hopiavuori, A, Fu, Z, Ward, N, Clarke, O, Shen, Y, Zhang, Y, Hendrickson, W.A, Yang, T.
登録日2020-02-21
公開日2020-04-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural and functional characterization of the bestrophin-2 anion channel.
Nat.Struct.Mol.Biol., 27, 2020
6WEJ
DownloadVisualize
BU of 6wej by Molmil
Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
著者Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
登録日2020-04-02
公開日2020-06-03
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
2B6B
DownloadVisualize
BU of 2b6b by Molmil
Cryo EM structure of Dengue complexed with CRD of DC-SIGN
分子名称: CD209 antigen, envelope glycoprotein
著者Pokidysheva, E, Zhang, Y, Battisti, A.J, Bator-Kelly, C.M, Chipman, P.R, Gregorio, G, Hendrickson, W.A, Kuhn, R.J, Rossmann, M.G.
登録日2005-09-30
公開日2006-03-07
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献Cryo-EM reconstruction of dengue virus in complex with the carbohydrate recognition domain of DC-SIGN
Cell(Cambridge,Mass.), 124, 2006
6O6M
DownloadVisualize
BU of 6o6m by Molmil
The Structure of EgtB (Cabther)
分子名称: EgtB (Cabther), FE (III) ION, GLYCEROL
著者Irani, S, Zhang, Y.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity.
Acs Catalysis, 9, 2019
5FBP
DownloadVisualize
BU of 5fbp by Molmil
CRYSTAL STRUCTURE OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH THE PRODUCT FRUCTOSE 6-PHOSPHATE AT 2.1-ANGSTROMS RESOLUTION
分子名称: 6-O-phosphono-beta-D-fructofuranose, FRUCTOSE 1,6-BISPHOSPHATASE
著者Ke, H, Liang, J.-Y, Zhang, Y, Lipscomb, W.N.
登録日1991-02-11
公開日1992-07-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the neutral form of fructose-1,6-bisphosphatase complexed with the product fructose 6-phosphate at 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon