6WF4

Crystal Structure of TerC Co-crystallized with Polyporic Acid

Summary for 6WF4

• Entry DOI: 10.2210/pdb6wf4/pdb
• Descriptor: Terfestatin Biosyntheis Enzyme C, (2~5~S)-2~3~,2~5~,2~6~-trihydroxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~(2~5~H)-one, ISOPROPYL ALCOHOL, ... (4 entities in total)
• Functional Keywords: natural products, jellyroll, structural genomics, psi-biology, enzyme discovery for natural product biosynthesis, natpro, biosynthetic protein
• Biological source: Streptomyces sp. RM-5-8
• Total number of polymer chains: 1
• Total formula weight: 20307.64

Authors

Clinger, J.A.,Miller, M.D.,Hall, R.E.,Zhang, Y.,Elshahawi, S.I.,Thorson, J.S.,Van Lanen, S.G.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2020-04-03, release date: 2021-04-07, Last modification date: 2023-10-18)

• Primary citation: Clinger, J.A.,Zhang, Y.,Liu, Y.,Miller, M.D.,Hall, R.E.,Van Lanen, S.G.,Phillips Jr., G.N.,Thorson, J.S.,Elshahawri, S.I.; Structural and functional characterization of two cooperative enzymes responsible for the stability of p-terphenyls.; To be published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)