6V4X

Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution

Summary for 6V4X

• Entry DOI: 10.2210/pdb6v4x/pdb
• EMDB information: 21045 21046 21047 21050
• Descriptor: Small nuclear ribonucleoprotein Sm D3, Symplekin, U7 snRNA, ... (13 entities in total)
• Functional Keywords: endonuclease, active cpsf73, u7 snrnp, 3'-end processing, ribonuclease, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 422255.18

Authors

Sun, Y.,Zhang, Y.,Walz, T.,Tong, L. (deposition date: 2019-12-02, release date: 2020-02-19, Last modification date: 2022-03-16)

• Primary citation: Sun, Y.,Zhang, Y.,Aik, W.S.,Yang, X.C.,Marzluff, W.F.,Walz, T.,Dominski, Z.,Tong, L.; Structure of an active human histone pre-mRNA 3'-end processing machinery.; Science, 367:700-703, 2020; PubMed: 32029631; DOI: 10.1126/science.aaz7758

Experimental method

ELECTRON MICROSCOPY (3.2 Å)