3EPO

Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P

Summary for 3EPO

Entry DOI	10.2210/pdb3epo/pdb
Related	3EPM 3EPN
Descriptor	Thiamine biosynthesis protein thiC, (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE (3 entities in total)
Functional Keywords	alpha-beta barrel, sam superfamily, thiamine biosynthesis, biosynthetic protein
Biological source	Caulobacter crescentus
Total number of polymer chains	2
Total formula weight	136550.55
Authors	Li, S.,Chatterjee, A.,Zhang, Y.,Grove, T.L.,Lee, M.,Krebs, C.,Booker, S.J.,Begley, T.P.,Ealick, S.E. (deposition date: 2008-09-29, release date: 2008-10-28, Last modification date: 2024-02-21)
Primary citation	Chatterjee, A.,Li, Y.,Zhang, Y.,Grove, T.L.,Lee, M.,Krebs, C.,Booker, S.J.,Begley, T.P.,Ealick, S.E. Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily Nat.Chem.Biol., 4:758-765, 2008 Cited by PubMed: 18953358 DOI: 10.1038/nchembio.121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation