7D76

Cryo-EM structure of the beclomethasone-bound adhesion receptor GPR97-Go complex

Summary for 7D76

• Entry DOI: 10.2210/pdb7d76/pdb
• EMDB information: 30602
• Descriptor: Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: gpcr, gpr97, complex, adhesion g protein-coupled receptor, membrane protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 136599.19

Authors

Ping, Y.,Mao, C.,Xiao, P.,Zhao, R.,Jiang, Y.,Yang, Z.,An, W.,Shen, D.,Yang, F.,Zhang, H.,Qu, C.,Shen, Q.,Tian, C.,Li, Z.,Li, S.,Wang, G.,Tao, X.,Wen, X.,Zhong, Y.,Yang, J.,Yi, F.,Yu, X.,Xu, E.,Zhang, Y.,Sun, J. (deposition date: 2020-10-03, release date: 2021-02-03, Last modification date: 2021-02-10)

• Primary citation: Ping, Y.Q.,Mao, C.,Xiao, P.,Zhao, R.J.,Jiang, Y.,Yang, Z.,An, W.T.,Shen, D.D.,Yang, F.,Zhang, H.,Qu, C.,Shen, Q.,Tian, C.,Li, Z.J.,Li, S.,Wang, G.Y.,Tao, X.,Wen, X.,Zhong, Y.N.,Yang, J.,Yi, F.,Yu, X.,Xu, H.E.,Zhang, Y.,Sun, J.P.; Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.; Nature, 589:620-626, 2021; PubMed: 33408414; DOI: 10.1038/s41586-020-03083-w

Experimental method

ELECTRON MICROSCOPY (3.1 Å)