6K0O
| The crystal structure of human CD163-like homolog SRCR8 | 分子名称: | Scavenger receptor cysteine-rich type 1 protein M160 | 著者 | Ma, H, Li, R, Jiang, L, Qiao, S, Zhang, G. | 登録日 | 2019-05-07 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro. Vet Res, 52, 2021
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6LM2
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6LPS
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7CJF
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | 著者 | Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. | 登録日 | 2020-07-10 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | 主引用文献 | A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun, 12, 2021
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2HFR
| solution structure of antimicrobial peptide Fowlicidin 3 | 分子名称: | Fowlicidin-3 | 著者 | Bommineni, Y.R, Dai, H, Gong, Y, Prakash, O, Zhang, G. | 登録日 | 2006-06-26 | 公開日 | 2007-04-17 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities. Febs J., 274, 2007
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2LQV
| YebF | 分子名称: | Protein yebF | 著者 | Prehna, G, Zhang, G, Gong, X, Duszyk, M, Okon, M, Mcintosh, L.P, Weiner, J.H, Strynadka, N.C.J. | 登録日 | 2012-03-16 | 公開日 | 2012-06-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A Protein Export Pathway Involving Escherichia coli Porins. Structure, 20, 2012
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8F5Q
| Crystal structure of human PCNA in complex with the PIP box of FBH1 | 分子名称: | F-box DNA helicase 1, Proliferating cell nuclear antigen | 著者 | Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T. | 登録日 | 2022-11-15 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular insight into the PCNA-binding mode of FBH1. Structure, 31, 2023
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7U15
| TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U16
| TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U17
| TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U10
| TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U11
| TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U13
| TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U12
| TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U18
| TMEM106B(120-254) T185S protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TMEM106B protein | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-20 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U0Z
| High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1 | 分子名称: | Isoform Tau-E of Microtubule-associated protein tau | 著者 | FItzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7U14
| TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | 登録日 | 2022-02-19 | 公開日 | 2022-03-23 | 最終更新日 | 2022-04-27 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases. Cell, 185, 2022
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7DEO
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... | 著者 | Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-04 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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7DET
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | 著者 | Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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7DEU
| Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | 著者 | Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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8IL3
| Cryo-EM structure of CD38 in complex with FTL004 | 分子名称: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy chain, Light chain | 著者 | Yang, J, Wang, Y, Zhang, G. | 登録日 | 2023-03-01 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma. J Hematol Oncol, 15, 2022
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3DXT
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3DXU
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8JNX
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2FRH
| Crystal Structure of Sara, A Transcription Regulator From Staphylococcus Aureus | 分子名称: | CALCIUM ION, Staphylococcal accessory regulator A | 著者 | Liu, Y, Manna, A.C, Ingavale, S, Cheung, A.L, Zhang, G. | 登録日 | 2006-01-19 | 公開日 | 2006-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus. Proc.Natl.Acad.Sci.Usa, 103, 2006
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