7DET

Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv

Summary for 7DET

• Entry DOI: 10.2210/pdb7det/pdb
• Related: 7DEO
• Descriptor: Spike protein S1, antibody scFv, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sars-cov-2, rbd, antibody, viral protein, antiviral protein, viral protein-antiviral protein complex, viral protein/antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 4
• Total formula weight: 107625.84

Authors

Wang, Y.,Zhang, G.,Li, X.,Rao, Z.,Guo, Y. (deposition date: 2020-11-05, release date: 2021-03-31, Last modification date: 2023-11-29)

• Primary citation: Fu, D.,Zhang, G.,Wang, Y.,Zhang, Z.,Hu, H.,Shen, S.,Wu, J.,Li, B.,Li, X.,Fang, Y.,Liu, J.,Wang, Q.,Zhou, Y.,Wang, W.,Li, Y.,Lu, Z.,Wang, X.,Nie, C.,Tian, Y.,Chen, D.,Wang, Y.,Zhou, X.,Wang, Q.,Yu, F.,Zhang, C.,Deng, C.,Zhou, L.,Guan, G.,Shao, N.,Lou, Z.,Deng, F.,Zhang, H.,Chen, X.,Wang, M.,Liu, L.,Rao, Z.,Guo, Y.; Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.; Plos Biol., 19:e3001209-e3001209, 2021; PubMed: 33961621; DOI: 10.1371/journal.pbio.3001209

Experimental method

X-RAY DIFFRACTION (2.2 Å)