6CHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cha by Molmil](/molmil-images/mine/6cha) | |
5HPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5hpg by Molmil](/molmil-images/mine/5hpg) | |
2SPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2spt by Molmil](/molmil-images/mine/2spt) | |
3HAT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hat by Molmil](/molmil-images/mine/3hat) | ACTIVE SITE MIMETIC INHIBITION OF THROMBIN | Descriptor: | FPAM (FIBRINOPEPTIDE A MIMIC), Hirudin variant-2, Thrombin heavy chain, ... | Authors: | Tulinsky, A, Mathews, I.I. | Deposit date: | 1994-10-16 | Release date: | 1995-02-27 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Active-site mimetic inhibition of thrombin. Acta Crystallogr.,Sect.D, 51, 1995
|
|
4HTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4htc by Molmil](/molmil-images/mine/4htc) | THE REFINED STRUCTURE OF THE HIRUDIN-THROMBIN COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... | Authors: | Tulinsky, A, Rydel, T.J, Bode, W, Huber, R. | Deposit date: | 1993-06-25 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Refined structure of the hirudin-thrombin complex. J.Mol.Biol., 221, 1991
|
|
2PK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2pk4 by Molmil](/molmil-images/mine/2pk4) | |
3HTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3htc by Molmil](/molmil-images/mine/3htc) | THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN | Descriptor: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN VARIANT 2 | Authors: | Tulinsky, A, Rydel, T.J, Ravichandran, K.G, Huber, R, Bode, W. | Deposit date: | 1993-06-11 | Release date: | 1994-01-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249, 1990
|
|
2HPP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hpp by Molmil](/molmil-images/mine/2hpp) | |
2HPQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hpq by Molmil](/molmil-images/mine/2hpq) | |
2HNT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hnt by Molmil](/molmil-images/mine/2hnt) | |
2HGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hgt by Molmil](/molmil-images/mine/2hgt) | |
1PK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pk4 by Molmil](/molmil-images/mine/1pk4) | |
1KGA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kga by Molmil](/molmil-images/mine/1kga) | |
1NRR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nrr by Molmil](/molmil-images/mine/1nrr) | |
1NRQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nrq by Molmil](/molmil-images/mine/1nrq) | |
1NRP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nrp by Molmil](/molmil-images/mine/1nrp) | |
1NRO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nro by Molmil](/molmil-images/mine/1nro) | |
1NRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nrn by Molmil](/molmil-images/mine/1nrn) | |
1NRS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nrs by Molmil](/molmil-images/mine/1nrs) | |
1DIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dit by Molmil](/molmil-images/mine/1dit) | COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN | Descriptor: | ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995 | Authors: | Tulinsky, A, Krishnan, R. | Deposit date: | 1995-07-20 | Release date: | 1996-06-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic. Protein Sci., 5, 1996
|
|
1CEA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cea by Molmil](/molmil-images/mine/1cea) | |
1HXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hxf by Molmil](/molmil-images/mine/1hxf) | |
1HXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hxe by Molmil](/molmil-images/mine/1hxe) | SERINE PROTEASE | Descriptor: | HIRUDIN VARIANT-1, RUBIDIUM ION, THROMBIN | Authors: | Tulinsky, A, Zhang, E. | Deposit date: | 1995-12-07 | Release date: | 1996-11-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The molecular environment of the Na+ binding site of thrombin. Biophys.Chem., 63, 1997
|
|
1FPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fpc by Molmil](/molmil-images/mine/1fpc) | ACTIVE SITE MIMETIC INHIBITION OF THROMBIN | Descriptor: | Hirudin, amino{[(4S)-4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)-5-(4-ethylpiperidin-1-yl)-5-oxopentyl]amino}methaniminium, thrombin | Authors: | Tulinsky, A, Mathews, I.I. | Deposit date: | 1994-10-16 | Release date: | 1995-02-27 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Active-site mimetic inhibition of thrombin. Acta Crystallogr.,Sect.D, 51, 1995
|
|
1HAO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hao by Molmil](/molmil-images/mine/1hao) | COMPLEX OF HUMAN ALPHA-THROMBIN WITH A 15MER OLIGONUCLEOTIDE GGTTGGTGTGGTTGG (BASED ON NMR MODEL OF DNA) | Descriptor: | ALPHA-THROMBIN heavy chain, ALPHA-THROMBIN light chain, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | Authors: | Tulinsky, A, Padmanabhan, K. | Deposit date: | 1995-10-03 | Release date: | 1996-04-03 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An ambiguous structure of a DNA 15-mer thrombin complex. Acta Crystallogr.,Sect.D, 52, 1996
|
|