1NRN

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES

Summary for 1NRN

DescriptorALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRS, ... (4 entities in total)
Functional Keywordsserine proteinase/receptor, serine proteinase-receptor complex
Biological sourceHomo sapiens (human)
Cellular locationSecreted, extracellular space P00734 P00734
Cell membrane; Multi-pass membrane protein P25116
Total number of polymer chains3
Total molecular weight36789.89
Authors
Tulinsky, A.,Mathews, I.I. (deposition date: 1994-01-18, release date: 1994-05-31, Last modification date: 2011-07-13)
Primary citation
Mathews, I.I.,Padmanabhan, K.P.,Ganesh, V.,Tulinsky, A.,Ishii, M.,Chen, J.,Turck, C.W.,Coughlin, S.R.,Fenton 2nd., J.W.
Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33:3266-3279, 1994
PubMed: 8136362 (PDB entries with the same primary citation)
DOI: 10.1021/bi00177a018
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers382.4%28.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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