3HAT

ACTIVE SITE MIMETIC INHIBITION OF THROMBIN

Replaces:  2HAT
Summary for 3HAT
DescriptorALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ... (5 entities in total)
Functional Keywordscomplex (serine protease-inhibitor), complex (serine protease-inhibitor) complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P09945
Total number of polymer chains4
Total formula weight36112.20
Authors
Tulinsky, A.,Mathews, I.I. (deposition date: 1994-10-16, release date: 1995-02-27, Last modification date: 2011-07-13)
Primary citationMathews, I.I.,Tulinsky, A.
Active-site mimetic inhibition of thrombin.
Acta Crystallogr.,Sect.D, 51:550-559, 1995
PubMed: 15299843
DOI: 110.1107/S0907444994013132
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation
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PDB entries from 2021-06-16