1NRS
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Summary for 1NRS
Entry DOI | 10.2210/pdb1nrs/pdb |
Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRP, ... (5 entities in total) |
Functional Keywords | serine proteinase, receptor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P09945 |
Total number of polymer chains | 4 |
Total formula weight | 35911.88 |
Authors | Tulinsky, A.,Mathews, I.I. (deposition date: 1994-01-18, release date: 1994-05-31, Last modification date: 2011-07-13) |
Primary citation | Mathews, I.I.,Padmanabhan, K.P.,Ganesh, V.,Tulinsky, A.,Ishii, M.,Chen, J.,Turck, C.W.,Coughlin, S.R.,Fenton 2nd., J.W. Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33:3266-3279, 1994 Cited by PubMed: 8136362DOI: 10.1021/bi00177a018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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