1NRS

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES

Summary for 1NRS
DescriptorALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE NRP, ... (5 entities in total)
Functional Keywordsserine proteinase, receptor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P09945
Total number of polymer chains4
Total formula weight35911.88
Authors
Tulinsky, A.,Mathews, I.I. (deposition date: 1994-01-18, release date: 1994-05-31, Last modification date: 2011-07-13)
Primary citationChen, J.,Coughlin, S.R.,Fenton 2nd., J.W.,Ganesh, V.,Ishii, M.,Mathews, I.I.,Padmanabhan, K.P.,Tulinsky, A.,Turck, C.W.
Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33:3266-3279, 1994
PubMed: 8136362
DOI: 110.1021/bi00177a018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation
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PDB entries from 2021-06-23