1DIT
COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN
Summary for 1DIT
| Entry DOI | 10.2210/pdb1dit/pdb |
| Descriptor | ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995, ... (4 entities in total) |
| Functional Keywords | hydrolase, blood coagulation, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted, extracellular space: P00734 P00734 |
| Total number of polymer chains | 3 |
| Total formula weight | 36010.99 |
| Authors | Tulinsky, A.,Krishnan, R. (deposition date: 1995-07-20, release date: 1996-06-10, Last modification date: 2023-11-15) |
| Primary citation | Krishnan, R.,Tulinsky, A.,Vlasuk, G.P.,Pearson, D.,Vallar, P.,Bergum, P.,Brunck, T.K.,Ripka, W.C. Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic. Protein Sci., 5:422-433, 1996 Cited by PubMed: 8868478PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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