1NRQ

CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES

Summary for 1NRQ

Entry DOI	10.2210/pdb1nrq/pdb
Descriptor	ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), RECEPTOR BASED PEPTIDE D-FPR'S (3 entities in total)
Functional Keywords	serine proteinase, receptor, hydrolase-hydrolase receptor complex, hydrolase/hydrolase receptor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P25116 Cell membrane; Multi-pass membrane protein: P00734
Total number of polymer chains	3
Total formula weight	36721.83
Authors	Tulinsky, A.,Mathews, I.I. (deposition date: 1994-01-18, release date: 1994-05-31, Last modification date: 2023-11-15)
Primary citation	Mathews, I.I.,Padmanabhan, K.P.,Ganesh, V.,Tulinsky, A.,Ishii, M.,Chen, J.,Turck, C.W.,Coughlin, S.R.,Fenton 2nd., J.W. Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33:3266-3279, 1994 Cited by PubMed: 8136362 DOI: 10.1021/bi00177a018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation