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PDB: 35 件

1LI1
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The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link
分子名称: ACETATE ION, Collagen alpha 1(IV), Collagen alpha 2(IV)
著者Than, M.E, Henrich, S, Huber, R, Ries, A, Mann, K, Kuhn, K, Timpl, R, Bourenkov, G.P, Bartunik, H.D, Bode, W.
登録日2002-04-17
公開日2002-05-22
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link.
Proc.Natl.Acad.Sci.USA, 99, 2002
1C52
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THERMUS THERMOPHILUS CYTOCHROME-C552: A NEW HIGHLY THERMOSTABLE CYTOCHROME-C STRUCTURE OBTAINED BY MAD PHASING
分子名称: CYTOCHROME-C552, PROTOPORPHYRIN IX CONTAINING FE
著者Than, M.E, Hof, P, Huber, R, Bourenkov, G.P, Bartunik, H.D, Buse, G, Soulimane, T.
登録日1997-06-23
公開日1998-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Thermus thermophilus cytochrome-c552: A new highly thermostable cytochrome-c structure obtained by MAD phasing.
J.Mol.Biol., 271, 1997
1S4V
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The 2.0 A crystal structure of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm
分子名称: DVA-LEU-LYS-0QE peptide, SULFATE ION, cysteine endopeptidase
著者Than, M.E, Helm, M, Simpson, D.J, Lottspeich, F, Huber, R, Gietl, C.
登録日2004-01-19
公開日2004-03-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 A crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm.
J.Mol.Biol., 336, 2004
4LXC
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The antimicrobial peptidase lysostaphin from Staphylococcus simulans
分子名称: Lysostaphin, SULFATE ION, ZINC ION
著者Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M.
登録日2013-07-29
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Febs J., 281, 2014
6EQW
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X-ray structure of the proprotein convertase furin bound with the competitive inhibitor 4-aminomethyl-phenylacetyl-Arg-Val-Arg-Amba
分子名称: AMA-ARG-TBG-ARG-00S, CALCIUM ION, CHLORIDE ION, ...
著者Dahms, S.O, Than, M.E.
登録日2017-10-16
公開日2018-02-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket.
Biochemistry, 57, 2018
6EQV
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X-ray structure of the proprotein convertase furin bound with the competitive inhibitor Phac-Cit-Val-Arg-Amba
分子名称: CALCIUM ION, CHLORIDE ION, Furin, ...
著者Dahms, S.O, Than, M.E.
登録日2017-10-16
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket.
Biochemistry, 57, 2018
1EHK
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BU of 1ehk by Molmil
CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS
分子名称: BA3-TYPE CYTOCHROME-C OXIDASE, COPPER (II) ION, DINUCLEAR COPPER ION, ...
著者Soulimane, T, Buse, G, Bourenkov, G.P, Bartunik, H.D, Huber, R, Than, M.E.
登録日2000-02-21
公開日2001-02-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from thermus thermophilus.
EMBO J., 19, 2000
5MIM
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BU of 5mim by Molmil
Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n
分子名称: 1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine, CALCIUM ION, CHLORIDE ION, ...
著者Dahms, S.O, Guan-Sheng, J, Than, M.E.
登録日2016-11-28
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.
ACS Chem. Biol., 12, 2017
5JXJ
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Structure of the proprotein convertase furin complexed to meta-guanidinomethyl-Phac-RVR-Amba in presence of EDTA
分子名称: 2UC-ARG-VAL-ARG-00S, CALCIUM ION, CHLORIDE ION, ...
著者Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E.
登録日2016-05-13
公開日2016-10-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JXI
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Structure of the unliganded form of the proprotein convertase furin in presence of EDTA.
分子名称: CALCIUM ION, CHLORIDE ION, Furin, ...
著者Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E.
登録日2016-05-13
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JXG
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BU of 5jxg by Molmil
Structure of the unliganded form of the proprotein convertase furin.
分子名称: CALCIUM ION, CHLORIDE ION, Furin, ...
著者Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E.
登録日2016-05-13
公開日2016-10-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JMR
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X-ray structure of the furin inhibitory antibody Nb14
分子名称: CHLORIDE ION, camelid VHH fragment
著者Dahms, S.O, Than, M.E.
登録日2016-04-29
公開日2016-12-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
Sci Rep, 6, 2016
5JMO
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X-ray structure of furin in complex with the inhibitory antibody Nb14
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CMK-inhibitor, ...
著者Dahms, S.O, Than, M.E.
登録日2016-04-29
公開日2016-12-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.
Sci Rep, 6, 2016
5JXH
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BU of 5jxh by Molmil
Structure the proprotein convertase furin in complex with meta-guanidinomethyl-Phac-RVR-Amba at 2.0 Angstrom resolution.
分子名称: 2UC-ARG-VAL-ARG-00S, CALCIUM ION, CHLORIDE ION, ...
著者Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E.
登録日2016-05-13
公開日2016-10-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
6EQX
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BU of 6eqx by Molmil
X-ray structure of the proprotein convertase furin bound with the competitive inhibitor Arg-Arg-Arg-Val-Arg-Amba
分子名称: Arg-Arg-Arg-Val-Arg-00S, CALCIUM ION, CHLORIDE ION, ...
著者Dahms, S.O, Than, M.E.
登録日2017-10-16
公開日2018-02-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献X-ray Structures of the Proprotein Convertase Furin Bound with Substrate Analogue Inhibitors Reveal Substrate Specificity Determinants beyond the S4 Pocket.
Biochemistry, 57, 2018
3QO4
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BU of 3qo4 by Molmil
The Crystal Structure of Death Receptor 6
分子名称: ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21
著者Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E.
登録日2011-02-09
公開日2011-05-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP).
J.Mol.Biol., 409, 2011
4QPB
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Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the absence of phosphate
分子名称: 1,2-ETHANEDIOL, Lysostaphin, ZINC ION
著者Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M.
登録日2014-06-22
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Febs J., 281, 2014
4RD9
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X-RAY STRUCTURE OF THE APO FORM OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN
分子名称: Amyloid-like protein 1
著者Dahms, S.O, Than, M.E.
登録日2014-09-18
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
Acta Crystallogr.,Sect.D, 71, 2015
4RDA
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X-RAY STRUCTURE OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN IN COMPLEX WITH A HEPARIN DODECASACCHARIDE
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Amyloid-like protein 1, ...
著者Dahms, S.O, Than, M.E.
登録日2014-09-18
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
Acta Crystallogr.,Sect.D, 71, 2015
4RYD
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BU of 4ryd by Molmil
X-ray structure of human furin in complex with the competitive inhibitor para-guanidinomethyl-Phac-R-Tle-R-Amba
分子名称: CALCIUM ION, FORMIC ACID, Furin, ...
著者Dahms, S.O, Than, M.E.
登録日2014-12-15
公開日2015-05-27
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Novel Furin Inhibitors with Potent Anti-infectious Activity.
Chemmedchem, 10, 2015
3KTM
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BU of 3ktm by Molmil
Structure of the Heparin-induced E1-Dimer of the Amyloid Precursor Protein (APP)
分子名称: (3R)-butane-1,3-diol, ACETATE ION, Amyloid beta A4 protein, ...
著者Dahms, S.O, Hoefgen, S, Roeser, D, Schlott, B, Guhrs, K.H, Than, M.E.
登録日2009-11-25
公開日2010-02-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein.
Proc.Natl.Acad.Sci.USA, 107, 2010
4OMC
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BU of 4omc by Molmil
X-ray structure of human furin in complex with the competitive inhibitor meta-guanidinomethyl-Phac-RVR-Amba
分子名称: CALCIUM ION, FORMIC ACID, Furin, ...
著者Dahms, S.O, Than, M.E.
登録日2014-01-27
公開日2014-04-09
最終更新日2014-05-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray Structures of Human Furin in Complex with Competitive Inhibitors.
Acs Chem.Biol., 9, 2014
4OMD
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X-ray structure of human furin in complex with the competitive inhibitor Phac-RVR-Amba
分子名称: CALCIUM ION, FORMIC ACID, Furin, ...
著者Dahms, S.O, Than, M.E.
登録日2014-01-27
公開日2014-04-09
最終更新日2014-05-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray Structures of Human Furin in Complex with Competitive Inhibitors.
Acs Chem.Biol., 9, 2014
4PWQ
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN of THE AMYLOID PRECURSOR PROTEIN
分子名称: Amyloid beta A4 protein
著者Hoefgen, S, Dahms, S.O, Than, M.E.
登録日2014-03-21
公開日2015-02-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Amyloid Precursor Protein Shows a pH-Dependent Conformational Switch in Its E1 Domain.
J.Mol.Biol., 427, 2015
4QP5
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Catalytic domain of the antimicrobial peptidase lysostaphin from Staphylococcus simulans crystallized in the presence of phosphate
分子名称: GLYCEROL, Lysostaphin, PHOSPHATE ION, ...
著者Sabala, I, Jagielska, E, Bardelang, P.T, Czapinska, H, Dahms, S.O, Sharpe, J.A, James, R, Than, M.E, Thomas, N.R, Bochtler, M.
登録日2014-06-22
公開日2014-07-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans.
Febs J., 281, 2014

 

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