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PDB: 85 件

1P3H
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Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 10 kDa chaperonin, CALCIUM ION
著者Roberts, M.M, Coker, A.R, Fossati, G, Mascagni, P, Coates, A.R.M, Wood, S.P, TB Structural Genomics Consortium (TBSGC)
登録日2003-04-17
公開日2003-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops
J.BACTERIOL., 185, 2003
5HVT
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Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2)
分子名称: 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Jorgensen, W.L.
登録日2016-01-28
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors.
J.Am.Chem.Soc., 138, 2016
7UL4
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CryoEM Structure of Inactive MOR Bound to Alvimopan and Mb6
分子名称: Megabody 6, Mu-type opioid receptor, N-[(2S)-2-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl}-3-phenylpropanoyl]glycine
著者Robertson, M.J, Skiniotis, G.
登録日2022-04-03
公開日2022-06-29
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure determination of inactive-state GPCRs with a universal nanobody.
Nat.Struct.Mol.Biol., 29, 2022
4WR8
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Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-180)
分子名称: 4-[4-(quinolin-2-yl)-1H-1,2,3-triazol-1-yl]phenol, Macrophage migration inhibitory factor, SODIUM ION, ...
著者Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L.
登録日2014-10-23
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor.
J.Am.Chem.Soc., 137, 2015
7UL2
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CryoEM Structure of Inactive NTSR1 Bound to SR48692 and Nb6
分子名称: 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Nanobody 6, Neurotensin receptor 1, ...
著者Robertson, M.J, Skiniotis, G.
登録日2022-04-03
公開日2022-06-29
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structure determination of inactive-state GPCRs with a universal nanobody.
Nat.Struct.Mol.Biol., 29, 2022
7UL5
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CryoEM Structure of Inactive SSTR2 bound to Nb6
分子名称: Nanobody 6, Somatostatin receptor type 2
著者Robertson, M.J, Skiniotis, G.
登録日2022-04-03
公開日2022-06-29
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure determination of inactive-state GPCRs with a universal nanobody.
Nat.Struct.Mol.Biol., 29, 2022
7UL3
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CryoEM Structure of Inactive H2R Bound to Famotidine, Nb6M, and NabFab
分子名称: Histamine H2 receptor, NabFab HC, NabFab LC, ...
著者Robertson, M.J, Skiniotis, G.
登録日2022-04-03
公開日2022-06-29
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure determination of inactive-state GPCRs with a universal nanobody.
Nat.Struct.Mol.Biol., 29, 2022
5J7Q
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Macrophage Migration Inhibitory Factor bound to Inhibitor K664 Derivative
分子名称: 4-(imidazo[1,2-a]pyridin-2-yl)benzene-1,2-diol, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Jorgensen, W.L.
登録日2016-04-06
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Irregularities in enzyme assays: The case of macrophage migration inhibitory factor.
Bioorg.Med.Chem.Lett., 26, 2016
5J7P
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Macrophage Migration Inhibitory Factor bound to Covalent Inhibitor RDR03785
分子名称: 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Jorgensen, W.L.
登録日2016-04-06
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Irregularities in enzyme assays: The case of macrophage migration inhibitory factor.
Bioorg.Med.Chem.Lett., 26, 2016
4WRB
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Macrophage Migration Inhibitory Factor in complex with a biaryltriazole inhibitor (3b-190)
分子名称: 4-{4-[6-(2-methoxyethoxy)quinolin-2-yl]-1H-1,2,3-triazol-1-yl}phenol, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Baxter, R.H.G, Jorgensen, W.L.
登録日2014-10-23
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor.
J.Am.Chem.Soc., 137, 2015
5HVS
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BU of 5hvs by Molmil
Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Biaryltriazole Inhibitor (3i-305)
分子名称: 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ...
著者Robertson, M.J, Jorgensen, W.L.
登録日2016-01-28
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors.
J.Am.Chem.Soc., 138, 2016
6CBG
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BU of 6cbg by Molmil
Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (5)
分子名称: 3-(1H-pyrazol-4-yl)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ...
著者Robertson, M.J, Krimmer, S.G, Jorgensen, W.L.
登録日2018-02-02
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor.
ChemMedChem, 13, 2018
6CBH
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Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (8m)
分子名称: 5-(3-fluoro-1H-pyrazol-4-yl)-2-[(naphthalen-2-yl)oxy]benzoic acid, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Robertson, M.J, Krimmer, S.G, Jorgensen, W.L.
登録日2018-02-02
公開日2018-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor.
ChemMedChem, 13, 2018
7T10
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CryoEM structure of somatostatin receptor 2 in complex with somatostatin-14 and Gi3
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-3, ...
著者Robertson, M.J, Skinotis, G.
登録日2021-11-30
公開日2022-03-09
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Plasticity in ligand recognition at somatostatin receptors.
Nat.Struct.Mol.Biol., 29, 2022
7T11
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BU of 7t11 by Molmil
CryoEM structure of somatostatin receptor 2 in complex with Octreotide and Gi3.
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-3, ...
著者Robertson, M.J, Skinotis, G.
登録日2021-11-30
公開日2022-03-09
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Plasticity in ligand recognition at somatostatin receptors.
Nat.Struct.Mol.Biol., 29, 2022
1XJR
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BU of 1xjr by Molmil
The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome
分子名称: MAGNESIUM ION, s2m RNA
著者Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G.
登録日2004-09-24
公開日2005-02-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
6CBF
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BU of 6cbf by Molmil
Macrophage Migration Inhibitory Factor in Complex with a Pyrazole Inhibitor (6a)
分子名称: 2-phenoxy-5-(1H-pyrazol-4-yl)benzoic acid, Macrophage migration inhibitory factor, SULFATE ION
著者Robertson, M.J, Krimmer, S.G, Jorgensen, W.L.
登録日2018-02-02
公開日2018-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor.
ChemMedChem, 13, 2018
2OIU
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BU of 2oiu by Molmil
L1 Ribozyme Ligase circular adduct
分子名称: L1 Ribozyme RNA Ligase, MAGNESIUM ION
著者Robertson, M.P, Scott, W.G.
登録日2007-01-11
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structural basis of ribozyme-catalyzed RNA assembly.
Science, 315, 2007
1LR2
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Crystal structure of thaumatin at high hydrostatic pressure
分子名称: L(+)-TARTARIC ACID, Thaumatin I
著者Charron, C, Kadri, A, Robert, M.C, Capelle, B, Giege, R, Lorber, B.
登録日2002-05-14
公開日2003-02-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray diffraction properties of protein crystals prepared in agarose gel under hydrostatic pressure.
J.CRYST.GROWTH, 245, 2002
1LR3
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Crystal structure of thaumatin at high hydrostatic pressure
分子名称: L(+)-TARTARIC ACID, Thaumatin I
著者Charron, C, Kadri, A, Robert, M.C, Capelle, B, Giege, R, Lorber, B.
登録日2002-05-14
公開日2003-02-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray diffraction properties of protein crystals prepared in agarose gel under hydrostatic pressure.
J.CRYST.GROWTH, 245, 2002
1U1U
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A. thaliana cobalamine independent methionine synthase
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION
著者Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R.
登録日2004-07-16
公開日2004-09-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate
J.Biol.Chem., 279, 2004
1U1H
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A. thaliana cobalamine independent methionine synthase
分子名称: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, SULFATE ION, ...
著者Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R.
登録日2004-07-15
公開日2004-09-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate
J.Biol.Chem., 279, 2004
1U22
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A. thaliana cobalamine independent methionine synthase
分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ...
著者Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R.
登録日2004-07-16
公開日2004-09-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate
J.Biol.Chem., 279, 2004
1U1J
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A. thaliana cobalamine independent methionine synthase
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, ...
著者Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R.
登録日2004-07-15
公開日2004-09-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate
J.Biol.Chem., 279, 2004
1LY0
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Structure of thaumatin crystallized in the presence of glycerol
分子名称: L(+)-TARTARIC ACID, Thaumatin I
著者Charron, C, Kadri, A, Robert, M.C, Giege, R, Lorber, B.
登録日2002-06-06
公開日2003-01-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Crystallization in the presence of glycerol displaces water molecules in the structure of thaumatin.
Acta Crystallogr.,Sect.D, 58, 2002

 

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