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PDB: 88 件
5HRT
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BU of 5hrt by Molmil
Crystal structure of mouse autotaxin in complex with a DNA aptamer
分子名称: CALCIUM ION, CHLORIDE ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ...
著者Kato, K, Nishimasu, H, Morita, J, Ishitani, R, Nureki, O.
登録日2016-01-24
公開日2016-04-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural basis for specific inhibition of Autotaxin by a DNA aptamer
Nat.Struct.Mol.Biol., 23, 2016
5GUH
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BU of 5guh by Molmil
Crystal structure of silkworm PIWI-clade Argonaute Siwi bound to piRNA
分子名称: MAGNESIUM ION, PIWI, RNA (28-MER)
著者Matsumoto, N, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2016-08-29
公開日2016-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA
Cell, 167, 2016
7VTI
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BU of 7vti by Molmil
Crystal structure of the Cas13bt3-crRNA binary complex
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
著者Nakagawa, R, Takeda, N.S, Tomita, A, Hirano, H, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O.
登録日2021-10-29
公開日2022-08-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure and engineering of the minimal type VI CRISPR-Cas13bt3.
Mol.Cell, 82, 2022
7VTN
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BU of 7vtn by Molmil
Cryo-EM structure of the Cas13bt3-crRNA-target RNA ternary complex
分子名称: Cas13bt3, crRNA, target RNA
著者Nakagawa, R, Soumya, K, Han, A, Takeda, N.S, Tomita, A, Hirano, H, Kusakizako, T, Tomohiro, N, Yamashita, K, Feng, Z, Nishimasu, H, Nureki, O.
登録日2021-10-30
公開日2022-09-07
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structure and engineering of the minimal type VI CRISPR-Cas13bt3.
Mol.Cell, 82, 2022
7WAH
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BU of 7wah by Molmil
Structure of Cas7-11 in complex with guide RNA and target RNA
分子名称: CRISPR-associated RAMP family protein, ZINC ION, crRNA (39-MER), ...
著者Kato, K, Okazaki, S, Isayama, Y, Nishizawa, T, Nishimasu, H.
登録日2021-12-14
公開日2022-06-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.
Cell, 185, 2022
7V94
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BU of 7v94 by Molmil
Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex
分子名称: Cas12c2, sgRNA, target DNA (non target strand), ...
著者Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O.
登録日2021-08-24
公開日2022-04-13
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structure of the type V-C CRISPR-Cas effector enzyme.
Mol.Cell, 82, 2022
7V93
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BU of 7v93 by Molmil
Cryo-EM structure of the Cas12c2-sgRNA binary complex
分子名称: cas12c2, sgRNA
著者Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O.
登録日2021-08-24
公開日2022-04-13
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the type V-C CRISPR-Cas effector enzyme.
Mol.Cell, 82, 2022
3A26
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BU of 3a26 by Molmil
Crystal structure of P. horikoshii TYW2 in complex with MeSAdo
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, TETRAETHYLENE GLYCOL, Uncharacterized protein PH0793
著者Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2009-04-28
公開日2009-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc.Natl.Acad.Sci.USA, 106, 2009
7V6B
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BU of 7v6b by Molmil
Structure of the Dicer-2-R2D2 heterodimer
分子名称: Dicer-2, isoform A, R2D2
著者Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
登録日2021-08-20
公開日2022-03-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
7V6C
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BU of 7v6c by Molmil
Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex
分子名称: Dicer-2, isoform A, R2D2, ...
著者Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O.
登録日2021-08-20
公開日2022-03-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
3A25
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BU of 3a25 by Molmil
Crystal structure of P. horikoshii TYW2 in complex with AdoMet
分子名称: S-ADENOSYLMETHIONINE, Uncharacterized protein PH0793
著者Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2009-04-28
公開日2009-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc.Natl.Acad.Sci.USA, 106, 2009
5XUZ
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BU of 5xuz by Molmil
Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (CCCA PAM)
分子名称: 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*CP*CP*CP*A)-3'), ...
著者Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2017-06-26
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
Mol. Cell, 67, 2017
3A27
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BU of 3a27 by Molmil
Crystal structure of M. jannaschii TYW2 in complex with AdoMet
分子名称: S-ADENOSYLMETHIONINE, Uncharacterized protein MJ1557
著者Umitsu, M, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2009-04-28
公開日2009-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc.Natl.Acad.Sci.USA, 106, 2009
4GTW
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BU of 4gtw by Molmil
Crystal structure of mouse Enpp1 in complex with AMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTZ
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BU of 4gtz by Molmil
Crystal structure of mouse Enpp1 in complex with CMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.191 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTY
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BU of 4gty by Molmil
Crystal structure of mouse Enpp1 in complex with GMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTX
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BU of 4gtx by Molmil
Crystal structure of mouse Enpp1 in complex with TMP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Kato, K, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-08-29
公開日2012-11-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.201 Å)
主引用文献Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
6AEK
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BU of 6aek by Molmil
Crystal structure of ENPP1 in complex with pApG
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
著者Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O.
登録日2018-08-05
公開日2019-03-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
Nat Commun, 9, 2018
6KR6
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BU of 6kr6 by Molmil
Crystal structure of Drosophila Piwi
分子名称: MERCURY (II) ION, Protein piwi, ZINC ION, ...
著者Yamaguchi, S, Oe, A, Yamashita, K, Hirano, S, Mastumoto, N, Ishitani, R, Nishimasu, H, Nureki, O.
登録日2019-08-21
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of Drosophila Piwi.
Nat Commun, 11, 2020
6AEL
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BU of 6ael by Molmil
Crystal structure of ENPP1 in complex with 3'3'-cGAMP
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, ...
著者Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O.
登録日2018-08-05
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
Nat Commun, 9, 2018
4YBG
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BU of 4ybg by Molmil
Crystal structure of the MAEL domain of Drosophila melanogaster Maelstrom
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Protein maelstrom, ...
著者Matsumoto, N, Ishitani, R, Nishimasu, H, Nureki, O.
登録日2015-02-18
公開日2015-04-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom
Cell Rep, 11, 2015
5B2O
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BU of 5b2o by Molmil
Crystal structure of Francisella novicida Cas9 in complex with sgRNA and target DNA (TGG PAM)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Hirano, H, Nishimasu, H, Nakane, T, Ishitani, R, Nureki, O.
登録日2016-02-01
公開日2016-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and Engineering of Francisella novicida Cas9
Cell, 164, 2016
5B2Q
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BU of 5b2q by Molmil
Crystal structure of Francisella novicida Cas9 RHA in complex with sgRNA and target DNA (TGG PAM)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Hirano, H, Nishimasu, H, Nakane, T, Ishitani, R, Nureki, O.
登録日2016-02-01
公開日2016-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and Engineering of Francisella novicida Cas9
Cell, 164, 2016
5B43
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BU of 5b43 by Molmil
Crystal structure of Acidaminococcus sp. Cpf1 in complex with crRNA and target DNA
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cpf1, DNA (34-MER), ...
著者Yamano, T, Nishimasu, H, Hirano, H, Nakane, T, Ishitani, R, Nureki, O.
登録日2016-03-30
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
Cell, 165, 2016
5B2P
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BU of 5b2p by Molmil
Crystal structure of Francisella novicida Cas9 in complex with sgRNA and target DNA (TGA PAM)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Hirano, H, Nishimasu, H, Nakane, T, Ishitani, R, Nureki, O.
登録日2016-02-01
公開日2016-03-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and Engineering of Francisella novicida Cas9
Cell, 164, 2016

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