7WAH

Structure of Cas7-11 in complex with guide RNA and target RNA

Summary for 7WAH

• Entry DOI: 10.2210/pdb7wah/pdb
• EMDB information: 32385
• Descriptor: crRNA (39-MER), tgRNA (5'-R(P*UP*AP*CP*CP*CP*AP*UP*GP*UP*CP*GP*AP*AP*GP*AP*CP*AP*AP*CP*AP*AP*AP*G)-3'), CRISPR-associated RAMP family protein, ... (4 entities in total)
• Functional Keywords: crispr, rnase, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 3
• Total formula weight: 205751.40

Authors

Kato, K.,Okazaki, S.,Isayama, Y.,Nishizawa, T.,Nishimasu, H. (deposition date: 2021-12-14, release date: 2022-06-15, Last modification date: 2024-06-26)

• Primary citation: Kato, K.,Zhou, W.,Okazaki, S.,Isayama, Y.,Nishizawa, T.,Gootenberg, J.S.,Abudayyeh, O.O.,Nishimasu, H.; Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.; Cell, 185:2324-2337.e16, 2022; PubMed: 35643083; DOI: 10.1016/j.cell.2022.05.003

Experimental method

ELECTRON MICROSCOPY (2.45 Å)