5XUZ

Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (CCCA PAM)

Summary for 5XUZ

• Entry DOI: 10.2210/pdb5xuz/pdb
• Descriptor: LbCpf1, crRNA, DNA (29-MER), ... (8 entities in total)
• Functional Keywords: nuclease, hydrolase-rna-dna complex, hydrolase, hydrolase/rna/dna
• Biological source: Lachnospiraceae bacterium ND2006; More
• Total number of polymer chains: 8
• Total formula weight: 337581.32

Authors

Yamano, T.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2017-06-26, release date: 2017-08-09, Last modification date: 2023-11-22)

• Primary citation: Yamano, T.,Zetsche, B.,Ishitani, R.,Zhang, F.,Nishimasu, H.,Nureki, O.; Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.; Mol. Cell, 67:633-645.e3, 2017; PubMed: 28781234; DOI: 10.1016/j.molcel.2017.06.035

Experimental method

X-RAY DIFFRACTION (2.4 Å)