4GTW

Crystal structure of mouse Enpp1 in complex with AMP

Summary for 4GTW

Entry DOI	10.2210/pdb4gtw/pdb
Related	4GTX 4GTY 4GTZ
Descriptor	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	bone mineralization, phosphodiesterase, hydrolase
Biological source	Mus musculus (mouse) More
Total number of polymer chains	2
Total formula weight	193664.34
Authors	Kato, K.,Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2012-08-29, release date: 2012-11-07, Last modification date: 2020-07-29)
Primary citation	Kato, K.,Nishimasu, H.,Okudaira, S.,Mihara, E.,Ishitani, R.,Takagi, J.,Aoki, J.,Nureki, O. Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc.Natl.Acad.Sci.USA, 109:16876-16881, 2012 Cited by PubMed: 23027977 DOI: 10.1073/pnas.1208017109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation