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5B43

Crystal structure of Acidaminococcus sp. Cpf1 in complex with crRNA and target DNA

Summary for 5B43
Entry DOI10.2210/pdb5b43/pdb
DescriptorCRISPR-associated endonuclease Cpf1, RNA (43-MER), DNA (34-MER), ... (7 entities in total)
Functional Keywordsnuclease, hydrolase-rna-dna complex, hydrolase/rna/dna
Biological sourceAcidaminococcus sp. BV3L6
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Total number of polymer chains4
Total formula weight179105.26
Authors
Yamano, T.,Nishimasu, H.,Hirano, H.,Nakane, T.,Ishitani, R.,Nureki, O. (deposition date: 2016-03-30, release date: 2016-05-04, Last modification date: 2024-03-20)
Primary citationYamano, T.,Nishimasu, H.,Zetsche, B.,Hirano, H.,Slaymaker, I.M.,Li, Y.,Fedorova, I.,Nakane, T.,Makarova, K.S.,Koonin, E.V.,Ishitani, R.,Zhang, F.,Nureki, O.
Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA
Cell, 165:949-962, 2016
Cited by
PubMed: 27114038
DOI: 10.1016/j.cell.2016.04.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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